ArticleBMC nephrology2013
Alcohol consumption is inversely associated with stage 3 chronic kidney disease in middle-aged Taiwanese men.
Article in BMC nephrology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
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The trial behind it
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Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it, 38 citations in OpenAlex.
- Dietary patterns and chronic kidney disease risk: a systematic review and updated meta-analysis of observational studies.Nutrition journal · 2021Pooled it
- Alcohol use disorder tied to development of chronic kidney disease: A nationwide database analysis.PloS one · 2018Trial
- Association between alcohol consumption and renal function in patients with diabetes mellitus and hypertension: insights from the Taiwan Biobank.BMC nephrology · 2025Observational
- Observational
- Prediction of incident chronic kidney disease in a population with normal renal function and normo-proteinuria.PloS one · 2023Article
- Association of alcohol consumption with the prevalence and various stages of chronic kidney disease.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2023Article
- Association of alcohol consumption with the incidence of proteinuria and chronic kidney disease: a retrospective cohort study in Japan.Nutrition journal · 2022Article
- Cardiovascular and renal burdens among patients with MAFLD and NAFLD in China.Frontiers in endocrinology · 2022Article
- J-shaped Relationship Between Chronic Kidney Disease and Serum Uric Acid Levels: A Cross-sectional Study on the Korean Population.Journal of rheumatic diseases · 2021Article
- Causal effect of alcohol use on the risk of end-stage kidney disease and related comorbidities: a Mendelian randomization study.Kidney research and clinical practice · 2021Article
- Effect of alcohol consumption on kidney function: population-based cohort study.Scientific reports · 2021Article
- Alcohol Consumption Can be a "Double-Edged Sword" for Chronic Kidney Disease Patients.Medical science monitor : international medical journal of experimental and clinical research · 2019Review
- Alcohol Consumption and Risk of Chronic Kidney Disease: A Nationwide Observational Cohort Study.Nutrients · 2019Observational
- Association between alcohol intake and measures of incident CKD: An analysis of nationwide health screening data.PloS one · 2019Article
- The association of alcohol and smoking with CKD in a Japanese nationwide cross-sectional survey.Hypertension research : official journal of the Japanese Society of Hypertension · 2017Article
- Effects of dietary interventions on incidence and progression of CKD.Nature reviews. Nephrology · 2014Review
Corrections and comments
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Authors and funding
5 authors at 5 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundChronic kidney disease (CKD) is a major global public health burden, but there is limited understanding of the relationship of alcohol consumption with CKD.
methodsIn this cross-sectional multivariable study, all participants of a health check-up program in Ditmanson Medical Foundation Chia-Yi Christian Hospital in Taiwan from 2003 to 2009 (15,353 women and 11,900 men) were included for analysis. Estimated glomerular filtration rate was used to define CKD stage and history of alcohol consumption was obtained by self-reporting. Multivariable logistic regression analyses of gender-specific association of alcohol drinking with stage 3 CKD were conducted. A trend tests was conducted to check the dose-response relationship of alcohol consumption with renal disease. A sensitivity test was conducted to rule out the likelihood of reverse causality.
resultsThe prevalence of stage 3 CKD was lower in drinkers than non-drinkers (p < 0.001) and the percentage of drinkers with stage 3 CKD was less than that of non-drinkers. Multivariable analysis indicated that alcohol consumption was negatively associated with the presence of stage 3 CKD in men (adjusted odds ratio [aOR] for occasional drinking: 0.68, 95% CI: 0.59 ~ 0.78, p < 0.001; aOR for frequent drinking: 0.47, 95% CI: 0.35 ~ 0.63, p < 0.001). Advanced age, hypertension, anemia, BMI of at least 24, hyperuricemia, and proteinuria were also associated with stage 3 CKD in men. Trend tests indicated lower odds of having stage 3 CKD with increased alcohol consumption in both genders. Subgroup analyses and sensitivity tests also indicated the reverse association between alcohol consumption and stage 3 CKD in men regardless of age, diabetes status, and other risky behaviors.
conclusionsAlcohol consumption was inversely associated with stage 3 CKD in Taiwanese men. However, considering the potential of other health damage with alcohol consumption, the current results should be interpreted cautiously.
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