Evidence map›Paper›PMID 24238335›Full record

ArticleImmunity2013

Septic shock: on the importance of being tolerant.

Ruslan Medzhitov

Open access · bronzeAbstract readComment
PubMed Publisher
In one paragraph

Article in Immunity, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 25 citations in OpenAlex.

  1. Autophagy induced by taurolidine protects against polymicrobial sepsis by promoting both host resistance and disease tolerance.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  2. Article
  3. Protein kinase C-delta inhibition is organ-protective, enhances pathogen clearance, and improves survival in sepsis.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2020
    Article
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  7. Review
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Ruslan MedzhitovHoward Hughes Medical Institute, New Haven, CT 06510 USA; Yale University School of Medicine, New Haven, CT 06510 USA. Electronic address: ruslan.medzhitov@yale.edu.
Howard Hughes Medical Institute · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A study by Figueiredo et al. (2013) in this issue of Immunity demonstrates that administration of anthracyclines induces autophagy in vivo and has a powerful protective effect in a mouse model of sepsis.

Indexed as

AnimalsAnthracyclinesAnti-Bacterial AgentsAtaxia Telangiectasia Mutated ProteinsDNA RepairLungPeritonitisSepsisAnthracyclinesAnti-Bacterial AgentsAtaxia Telangiectasia Mutated ProteinsAtm protein, mouse

Identifiers

PMID24238335
OpenAlexW2030706519

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.