ArticleSurgery2013
Timing of symptom improvement after parathyroidectomy for primary hyperparathyroidism.
Article in Surgery, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
8 citing papers in PubMed.
- Improvement of sleep disturbance and insomnia following parathyroidectomy for primary hyperparathyroidism.World journal of surgery · 2014Trial
- Neuropsychiatric manifestations of primary hyperparathyroidism.Wiener klinische Wochenschrift · 2026Review
- The impact of patient age on practice patterns and outcomes for primary hyperparathyroidism.American journal of surgery · 2022Article
- Irisin and Secondary Osteoporosis in Humans.International journal of molecular sciences · 2022Review
- Physical Activity-Dependent Regulation of Parathyroid Hormone and Calcium-Phosphorous Metabolism.International journal of molecular sciences · 2020Review
- Should Symptoms Be Considered an Indication for Parathyroidectomy in Primary Hyperparathyroidism?Clinical medicine insights. Endocrinology and diabetes · 2018Review
- Primary hyperparathyroidism.Ulusal cerrahi dergisi · 2016Review
- Elevated parathyroid hormone after parathyroidectomy delays symptom improvement.The Journal of surgical research · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
Abstract
backgroundThe timing of symptom improvement after parathyroidectomy for primary hyperparathyroidism (PHPT) has not been well characterized.
methodsThis prospective study involved administering a questionnaire to patients with PHPT who underwent curative parathyroidectomy over an 11-month period. The questionnaire evaluated the frequency of 18 symptoms of PHPT on a 5-point Likert scale and was administered preoperatively and 1 week, 6 weeks, and 6 months postoperatively.
resultsOf 197 eligible patients, 132 (67%) participated in the study. The questionnaires were completed at a rate of 91%, 92%, and 86% at 1 week, 6 weeks, and 6 months postoperatively, respectively. The most commonly reported preoperative symptoms were fatigue (98%), muscle aches (89%), and bone/joint pain (87%). Improvement in symptom severity occurred across all symptoms and was separated into three categories based on the timing of improvement. Fatigue and bone/joint pain demonstrated "Immediate Improvement" (>50% of patients reporting improvement by post-operative week 1), whereas the majority of symptoms showed peak improvement at 6 weeks ("Delayed Improvement"). Symptoms categorized as "Continuous Improvement" were those showing progressive improvement up to 6 months postoperatively (polydipsia, headaches, and nausea/vomiting).
conclusionSymptom improvement was most prominent 6 weeks postparathyroidectomy, although some symptoms showed continued improvement at 6 months.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.