Evidence map›Paper›PMID 24237984›Full record

ReviewPediatric clinics of North America2013

Diagnosis and management of autoimmune cytopenias in childhood.

David T Teachey, Michele P Lambert

Open access · greenAbstract readReview
In one paragraph

Review in Pediatric clinics of North America, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed
4.2field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 93 citations in OpenAlex.

  1. Article
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  10. La Tunisie medicale · 2024
    Article
  11. Article
  12. Article
  13. Article
  14. Human adenovirus associated with severe cold agglutinin syndrome: a rare complication in Pediatrics.Revista paulista de pediatria : orgao oficial da Sociedade de Pediatria de Sao Paulo · 2023
    Article
  15. Cold AIHA and the best treatment strategies.Hematology. American Society of Hematology. Education Program · 2022
    Article
  16. Article
  17. Review
  18. Article
  19. Response to rituximab in children and adults with immune thrombocytopenia (ITP).Research and practice in thrombosis and haemostasis · 2021
    Article
  20. Autoimmune Hemolytic Anemia in the Pediatric Setting.Journal of clinical medicine · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

David T TeacheyPediatric Hematology, Children's Hospital of Philadelphia, University of Pennsylvania School of Medicine, 3501 Civic Center Boulevard, Philadelphia, PA 19104, USA. Electronic address: teacheyd@email.chop.edu.
Michele P Lambert
Philadelphia University · US

Funding

Targeting Akt signaling in Autoimmune Lymphoproliferative SyndromeR21AI099301 · NIAID · CHILDREN'S HOSP OF PHILADELPHIA · PI TEACHEY, DAVID T. · 2012 to 2013
$463k
NIAID NIH HHS R21 AI099301
6 · The paper itself

Abstract

The diagnosis and management of children with autoimmune cytopenias can be challenging. Children can present with immune-mediated destruction of a single-cell lineage or multiple cell lineages, including platelets (immune thrombocytopenia [ITP]), erythrocytes (autoimmune hemolytic anemia), and neutrophils (autoimmune neutropenia). Immune-mediated destruction can be primary or secondary to a comorbid immunodeficiency, malignancy, rheumatologic condition, or lymphoproliferative disorder. Treatment options generally consist of nonspecific immune suppression or modulation. This nonspecific approach is changing as recent insights into disease biology have led to targeted therapies, including the use of thrombopoietin mimetics in ITP and sirolimus for cytopenias associated with autoimmune lymphoproliferative syndrome.

Indexed as

Anemia, Hemolytic, AutoimmuneChildHumansImmunologic FactorsImmunotherapyNeutropeniaThrombocytopeniaImmunologic FactorsAutoimmune hemolytic anemiaAutoimmune lymphoproliferative syndromeAutoimmune neutropeniaEvans syndromeImmune thrombocytopenia

Identifiers

PMID24237984
PMCPMC5384653
OpenAlexW2004843421

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.