ArticleJournal of veterinary internal medicine
Clinical characterization of epilepsy of unknown cause in cats.
Article in Journal of veterinary internal medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Systematic review of antiepileptic drugs' safety and effectiveness in feline epilepsy.BMC veterinary research · 2018Pooled it
- Imepitoin is well tolerated in healthy and epileptic cats.BMC veterinary research · 2017Trial
- Epileptic seizures in cats: practical approaches to diagnosis.Journal of feline medicine and surgery · 2026Review
- Clinical and Diagnostic Features of Feline Epilepsy: Distribution of Seizure Types and Associated Factors.Animals : an open access journal from MDPI · 2025Article
- Use of video-electroencephalography as a first-line examination in veterinary neurology: development and standardization of electroencephalography in unsedated dogs and cats.Frontiers in veterinary science · 2024Article
- Once-a-day oral treatment with phenobarbital in cats with presumptive idiopathic epilepsy.Journal of feline medicine and surgery · 2023Article
- Parallel roles of neuroinflammation in feline and human epilepsies.Veterinary journal (London, England : 1997) · 2022Review
- Phenotypic characterisation of paroxysmal dyskinesia in Sphynx cats.Journal of feline medicine and surgery · 2022Article
- Epilepsy in British Shorthair cats in Sweden.Journal of feline medicine and surgery · 2022Article
- Feline temporal lobe epilepsy: seven cases of hippocampal and piriform lobe necrosis in England and literature review.Journal of feline medicine and surgery · 2022Review
- Article
- Benign juvenile idiopathic epilepsy in captive Iberian lynx (Lynx pardinus) in the ex situ conservation program (2005-2019).BMC veterinary research · 2021Article
- Prevalence and clinical characteristics of phenobarbitone-associated adverse effects in epileptic cats.Journal of feline medicine and surgery · 2021Article
- Focal Cortical Resection and Hippocampectomy in a Cat With Drug-Resistant Structural Epilepsy.Frontiers in veterinary science · 2021Article
- Epidemiology of recurrent seizure disorders and epilepsy in cats under primary veterinary care in the United Kingdom.Journal of veterinary internal medicine · 2020Article
- Physiology and molecular biology of barrier mechanisms in the fetal and neonatal brain.The Journal of physiology · 2018Review
- Recurrent seizures in cats: Treatment - which antiepileptic drugs are recommended?Journal of feline medicine and surgery · 2018Review
- Recurrent seizures in cats: Diagnostic approach - when is it idiopathic epilepsy?Journal of feline medicine and surgery · 2018Article
- Molecular cloning and characterization of the family of feline leucine-rich glioma-inactivated (LGI) genes, and mutational analysis in familial spontaneous epileptic cats.BMC veterinary research · 2017Article
- Survival in 76 cats with epilepsy of unknown cause: a retrospective study.The Veterinary record · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe diagnosis of feline epilepsy of unknown cause (EUC) requires a thorough diagnostic evaluation, otherwise the prevalence of EUC could be overestimated. HYPOTHESIS: Feline EUC is a clinically defined disease entity, which differs from feline hippocampal necrosis by the absence of magnetic resonance imaging (MRI) signal alteration of the hippocampus. The objectives of this study were (1) to evaluate the prevalence of EUC in a hospital population of cats by applying well-defined inclusion criteria, and (2) to describe the clinical course of EUC. ANIMALS: Eighty-one cats with recurrent seizures.
methodsRetrospective study--medical records were reviewed for cats presented for evaluation of recurrent seizures (2005-2010). Inclusion criteria were a defined diagnosis based on laboratory data, and either MRI or histopathology. Final outcome was confirmed by telephone interview with the owner. Magnetic resonance images were reviewed to evaluate hippocampal morphology and signal alterations.
resultsEpilepsy of unknown cause was diagnosed in 22% of cats with epilepsy. Physical, neurologic, and laboratory examinations, and either 1.5 T MRI and cerebrospinal fluid analysis or postmortem examination failed to identify an underlying cause. Cats with EUC had a higher survival rate (P < .05) and seizure remission occurred frequently (44.4%). CONCLUSION AND CLINICAL IMPORTANCE: A detailed clinical evaluation and diagnostic imaging with MRI is recommended in any cat with recurrent seizures. The prognosis of cats with normal MRI findings and a clinical diagnosis of EUC are good. Standardized imaging guidelines should be established to assess the hippocampus in cats.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.