ArticleJournal of comparative effectiveness research2012
Comparative effectiveness of renin-angiotensin system inhibitors in hypertension.
Article in Journal of comparative effectiveness research, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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0 citing papers in PubMed, 2 citations in OpenAlex.
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1 author at 1 institution in 1 country.
Funding
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Abstract
Hypertension is a chronic problem in the USA and there are three main ways to block the renin-angiotensin system: direct renin inhibitors, angiotensin-converting enzyme inhibitors (ACEIs) and angiotensin receptor blockers (ARBs). This article is a summary of a direct comparative effectiveness review of direct comparative trials in patients with hypertension. In patients with hypertension, ACEIs and ARBs provide similar blood pressure effects and no differences were seen in final health outcomes. ARBs have less ACE-induced cough and fewer withdrawals due to adverse events. Direct renin inhibitors versus ACE inhibitors or ARBs have not been extensively studied and their role is less clear.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.