Evidence map›Paper›PMID 24236160›Full record

ArticlePloS one2013

Association of diabetes in pregnancy with child weight at birth, age 12 months and 5 years--a population-based electronic cohort study.

Kelly Morgan, Mohammed Rahman, Mark Atkinson, Shang-Ming Zhou, Rebecca Hill, Ashrafunnesa Khanom, Shantini Paranjothy, Sinead Brophy

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Kelly MorganCollege of Medicine, Swansea University, Swansea, Wales, United Kingdom.
Mohammed Rahman
Mark Atkinson
Shang-Ming Zhou
Rebecca Hill
Ashrafunnesa Khanom
Shantini Paranjothy
Sinead Brophy
Swansea University · GBGower College Swansea · GBCardiff University · GB

Funding

Medical Research Council MR/K006525/1
6 · The paper itself

Abstract

backgroundThis study examines the effect of diabetes in pregnancy on offspring weight at birth and ages 1 and 5 years.

methodsA population-based electronic cohort study using routinely collected linked healthcare data. Electronic medical records provided maternal diabetes status and offspring weight at birth and ages 1 and 5 years (n = 147,773 mother child pairs). Logistic regression models were used to obtain odds ratios to describe the association between maternal diabetes status and offspring size, adjusted for maternal pre-pregnancy weight, age and smoking status.

findingsWe identified 1,250 (0.9%) pregnancies with existing diabetes (27.8% with type 1 diabetes), 1,358 with gestational diabetes (0.9%) and 635 (0.4%) who developed diabetes post-pregnancy. Children whose mothers had existing diabetes were less likely to be large at 12 months (OR: 0.7 (95%CI: 0.6, 0.8)) than those without diabetes. Maternal diabetes was associated with high weight at age 5 years in children whose mothers had a high pre-pregnancy weight tertile (gestational diabetes, (OR:2.1 (95%CI:1.25-3.6)), existing diabetes (OR:1.3 (95%CI:1.0 to 1.6)).

conclusionThe prevention of childhood obesity should focus on mothers with diabetes with a high maternal pre-pregnancy weight. We found little evidence that diabetes in pregnancy leads to long term obesity 'programming'.

Indexed as

Body WeightDiabetes, GestationalPopulation SurveillanceBirth WeightChild, PreschoolCohort StudiesFemaleHumansInfantInfant, NewbornMaleOdds RatioPediatric ObesityPregnancyPrevalenceRisk Factors

Identifiers

PMID24236160
PMCPMC3827417
OpenAlexW2094073393

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.