SynthesisJournal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine2013
The relationship between depressive symptoms and obstructive sleep apnea in pediatric populations: a meta-analysis.
Synthesis in Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
26 citing papers in PubMed, 2 syntheses or guidelines pooled it, 79 citations in OpenAlex.
- An Interdisciplinary Approach: Presentation of the Pediatric Obstructive Sleep Apnea Diagnostic Examination Form (POSADEF).Diagnostics (Basel, Switzerland) · 2024Guideline
- Prader Willi syndrome and obstructive sleep apnea: co-occurrence in the pediatric population.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2014Pooled it
- Do Sleep Disturbances Improve Following Psychoanalytic Psychotherapy for Adolescent Depression?International journal of environmental research and public health · 2022Trial
- Trial
- Assessing subtle brain injury related to cognitive impairment in obese pediatric obstructive sleep apnea using 3D MRI texture analysis.Scientific reports · 2026Article
- Differences in attention abilities, growth, development, and quality of life between Chinese children with obstructive sleep apnea and healthy controls.The Journal of international medical research · 2025Article
- Obstructive Sleep Apnea in Pediatrics and Adolescent Women: A Systematic Review of Sex-Based Differences Between Girls and Boys.Children (Basel, Switzerland) · 2024Review
- Nasal obstruction during development leads to defective synapse elimination, hypersynchrony, and impaired cerebellar function.Communications biology · 2024Article
- Undergraduate dental sleep medicine teaching at German university dental schools - a questionnaire-based survey.BMC medical education · 2024Article
- Psychological Mechanisms of Internalized HIV Stigma Affect Sleep Impairment among People Living with HIV in China: A follow-up Study.AIDS and behavior · 2024Article
- A Pediatric Patient with Severe Obstructive Sleep Apnea and Comorbid Depression and Substance Abuse.Case reports in psychiatry · 2023Article
- The impact of the COVID-19 pandemic on positive airway pressure usage in children with sleep-disordered breathing.Sleep & breathing = Schlaf & Atmung · 2022Article
- Behavioral, neurocognitive, polysomnographic and cardiometabolic profiles associated with obstructive sleep apnea in adolescents with ADHD.Journal of child psychology and psychiatry, and allied disciplines · 2022Article
- You Cannot Hit Snooze on OSA: Sequelae of Pediatric Obstructive Sleep Apnea.Children (Basel, Switzerland) · 2022Review
- Positive Airway Pressure Usage in Youth with Obstructive Sleep Apnea Following Transition to Adult Health Care.Nature and science of sleep · 2022Article
- Elevated risk of depression among adolescents presenting with sleep disorders.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2021Article
- Effect of adenotonsillectomy in children with obstructive sleep apnea and major psychiatric disorders on obstructive apnea-hypopnea index and Epworth Sleepiness Scale scores.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2021Article
- Sleep and Mood Disorders Among Youth.Child and adolescent psychiatric clinics of North America · 2021Review
- Prevalence of Sleep-Disordered Breathing in Children Referring for First Dental Examination. A Multicenter Cross-Sectional Study Using Pediatric Sleep Questionnaire.International journal of environmental research and public health · 2020Article
- Transition to Adult Care for Obstructive Sleep Apnea.Journal of clinical medicine · 2019Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundA higher incidence of depressive disorders and symptoms has been suggested among children suffering from obstructive sleep apnea (OSA). Yet, the extent to which OSA is related to increased depression is unclear.
objectivesTo evaluate (a) the relationship between depressive symptoms and OSA in pediatric populations, and (b) the efficacy of adenotonsillectomy (AT) for decreasing depressive symptoms among children with OSA.
methodsA meta-analysis was conducted to assess the relationship between depressive symptoms and OSA, and the efficacy of AT for decreasing depressive symptoms. Studies reporting depressive symptoms of children with OSA through January 2013 were included.
resultsEleven studies assessed depressive symptoms in both children diagnosed with OSA (n = 894) and a comparison group (n = 1,096). A medium relationship was found between depressive symptoms and OSA (Hedges' g = 0.43, 95% CI: 0.22-0.64; p = 0.0005). Addressing the second question, 9 studies (n = 379 children) examined depressive symptoms pre- and post-AT. A medium improvement in depressive symptoms was found at follow-up (Hedge's g = 0.41, 95% CI: 0.20-0.62; p ≤ 0.001).
conclusionOur findings suggest that depressive symptoms are higher among children with OSA. Therefore, patients with depressive symptomatology should receive screening for sleep disordered breathing. Treatment of OSA with AT might decrease clinical symptoms of depression, reduce pharmacotherapy, improve sleep patterns, and promote better health.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.