ReviewFrontiers of medicine2013
Heterogeneity of chronic obstructive pulmonary disease: from phenotype to genotype.
Review in Frontiers of medicine, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
11 citing papers in PubMed, 18 citations in OpenAlex.
- Rapid decline in lung function is associated with more chronic respiratory symptoms, more severe small airway dysfunction and lung structural changes.Journal of thoracic disease · 2026Article
- Incorporating External Information in Tissue Subtyping: A Topic Modeling Approach.Proceedings of machine learning research · 2021Article
- Energy efficient physiologic coupling of gait and respiration is altered in chronic obstructive pulmonary disease.Acta physiologica (Oxford, England) · 2019Article
- Evaluation OfInternational journal of chronic obstructive pulmonary disease · 2019Article
- Patients with Chronic Obstructive Pulmonary Disease Walk with Altered Step Time and Step Width Variability as Compared with Healthy Control Subjects.Annals of the American Thoracic Society · 2017Article
- Sulfatase modifying factor 1 (SUMF1) is associated with Chronic Obstructive Pulmonary Disease.Respiratory research · 2017Article
- Risk Perceptions in Diabetic Patients Who Have Experienced Adverse Events: Implications for Patient Involvement in Regulatory Decisions.Pharmaceutical medicine · 2017Article
- Gait mechanics in patients with chronic obstructive pulmonary disease.Respiratory research · 2015Article
- Utility of animal and in vivo experimental infection of humans with rhinoviruses in the development of therapeutic agents for viral exacerbations of asthma and chronic obstructive pulmonary disease.Pulmonary pharmacology & therapeutics · 2015Review
- Tailoring of corticosteroids in COPD management.Current respiratory care reports · 2014Review
- Knowledge Distillation via Constrained Variational Inference.Proceedings of the ... AAAI Conference on Artificial Intelligence. AAAI Conference on Artificial IntelligenceArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Chronic obstructive pulmonary disease (COPD) is one of the leading causes of morbidity and mortality throughout the world and is mainly characterized by persistent airflow limitation. Given that multiple systems other than the lung can be impaired in COPD patients, the traditional FEV1/FVC ratio shows many limitations in COPD diagnosis and assessment. Certain heterogeneities are found in terms of clinical manifestations, physiology, imaging findings, and inflammatory reactions in COPD patients; thus, phenotyping can provide effective information for the prognosis and treatment. However, phenotypes are often based on symptoms or pathophysiological impairments in late-stage COPD, and the role of phenotypes in COPD prevention and early diagnosis remains unclear. This shortcoming may be overcome by the potential genotypes defined by the heterogeneities in certain genes. This review briefly describes the heterogeneity of COPD, with focus on recent advances in the correlations between genotypes and phenotypes. The potential roles of these genotypes and phenotypes in the molecular mechanisms and management of COPD are also elucidated.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.