Evidence map›Paper›PMID 24234601›Full record

SynthesisAnnals of behavioral medicine : a publication of the Society of Behavioral Medicine2014

Depression treatment enhances adherence to antiretroviral therapy: a meta-analysis.

Nancy L Sin, M Robin DiMatteo

Registry-linked trialOpen access · bronzeAbstract readMeta-Analysis
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Annals of behavioral medicine : a publication of the Society of Behavioral Medicine, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06295250 (ASHA Bangladesh--An Integrated Intervention to Address Depression in Low Income Rural Women), which is not on this map. Cited by 154 papers, 15 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
154citing papers in PubMed, 15 pooled it
9.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06295250 narecruitingnot on this mapstarted 2024, after this paper: background citation

ASHA Bangladesh--An Integrated Intervention to Address Depression in Low Income Rural Women

TypeinterventionalSponsorUniversity of Massachusetts, WorcesterRan2024 to 2026Enrolled600ConditionsDepression, Economic Vulnerability, Anxiety, Culture Specific SymptomsArmsManualized Group Based Psychotherapy, Poverty Alleviation
3 · Its place in the literature

Who cites it

154 citing papers in PubMed, 15 syntheses or guidelines pooled it, 265 citations in OpenAlex.

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  7. Positive affect and medication adherence in chronic conditions: A systematic review.Health psychology : official journal of the Division of Health Psychology, American Psychological Association · 2019
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  10. Mental health and retention in HIV care: A systematic review and meta-analysis.Health psychology : official journal of the Division of Health Psychology, American Psychological Association · 2018
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94 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Nancy L Sin
M Robin DiMatteo
Pennsylvania State University · USUniversity of California, Riverside · US

Funding

VARC CoreP30AG044281 · NIA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Alexander Keliimoeanu Smith · 2013 to 2026
$19.9M
RESEARCH TRAINING IN GERIATRIC MEDICINET32AG000212 · NIA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Alexander Keliimoeanu Smith · 1991 to 2026
$7.7M
NIA NIH HHS 5T32AG000212-20NIA NIH HHS P30 AG044281NIA NIH HHS T32 AG000212
6 · The paper itself

Abstract

backgroundDepression is a risk factor for nonadherence to HIV/AIDS treatment. PURPOSE: A meta-analysis was conducted to examine whether treatment of depression and psychological distress improves antiretroviral therapy adherence.

methodsPubMed and PsycINFO databases were systematically searched for relevant articles. Studies that reported an association between depression treatment (or an intervention with a component addressing mental health) and antiretroviral adherence were included.

resultsAcross 29 studies of 12,243 persons living with HIV/AIDS, treatment of depression and psychological distress improved antiretroviral adherence (p < 0.001). The odds of a person adhering were 83 % better if he/she was treated for depression. Greater improvements in adherence were found for samples with lower CD4 counts or more severe depression, for interventions specifically targeting depression (versus addressing mental health as a secondary objective), longer treatments, and observational studies.

conclusionsThese findings support the need for detection and treatment of depression among persons living with HIV/AIDS.

Indexed as

Antidepressive AgentsAnti-Retroviral AgentsDepressionFemaleHIV InfectionsHumansMaleMedication AdherencePsychotherapyStress, PsychologicalTreatment OutcomeAntidepressive AgentsAnti-Retroviral Agents

Identifiers

PMID24234601
PMCPMC4021003
OpenAlexW2150023922

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.