Evidence map›Paper›PMID 24234451›Full record

ArticleNucleic acids research2014

The MIntAct project--IntAct as a common curation platform for 11 molecular interaction databases.

Sandra Orchard, Mais Ammari, Bruno Aranda, Lionel Breuza, Leonardo Briganti, Fiona Broackes-Carter, Nancy H Campbell, Gayatri Chavali, Carol Chen, Noemi del-Toro and 25 more

Abstract read
In one paragraph

Article in Nucleic acids research, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1,051 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1,051citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1,051 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
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  10. Proteogenomics in human populations.Nature reviews. Genetics · 2026
    Review
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991 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

35 authors.

Sandra OrchardEuropean Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, UK, School of Animal and Comparative Biomedical Sciences, The University of Arizona, Tucson, AZ 85721-0036, USA, Swiss-Prot Group, SIB Swiss Institute of Bioinformatics, CMU, 1 Rue Michel-Servet, CH-1211 Geneva 4, Switzerland, Department of Biology, University of Rome Tor Vergata, Rome 00133, Italy, Ontario Cancer Institute, the Campbell Family Institute for Cancer Research, and Techna Institute, University Health Network, Toronto, Ontario M5G 0A3, Canada, Cardiovascular Gene Annotation Initiative, Centre for Cardiovascular Genetics, Institute of Cardiovascular Science, University College London, London WC1E 6BT, UK, Centre for Microbial Diseases and Immunity Research, University of British Columbia, Vancouver, British Columbia V6T 1Z4 Canada, Mechanobiology Institute, National University of Singapore, T-Lab #05-01, 5A Engineering Drive 1, Singapore 117411, Singapore, Department of Cancer Research and Molecular Medicine, Norwegian University of Science and Technology, 7489 Trondheim, Norway, Research Institute IRCSS "Fondazione Santa Lucia", Rome 00179, Italy, Molecular Connections Pvt. Ltd., Bangalore 560 004, India, Institut de Biologie et Chimie des Protéines, Unité Mixte de Recherche 5086, Centre National de la Recherche Scientifique, Université Lyon 1, Lyon, France and Structural and Computational Biology Unit, European Molecular Biology Laboratory (EMBL), Meyerhofstrasse 1, D-69117 Heidelberg, Germany.
Mais Ammari
Bruno Aranda
Lionel Breuza
Leonardo Briganti
Fiona Broackes-Carter
Nancy H Campbell
Gayatri Chavali
Carol Chen
Noemi del-Toro
Margaret Duesbury
Marine Dumousseau
Eugenia Galeota
Ursula Hinz
Marta Iannuccelli
Sruthi Jagannathan
Rafael Jimenez
Jyoti Khadake
Astrid Lagreid
Luana Licata
Ruth C Lovering
Birgit Meldal
Anna N Melidoni
Mila Milagros
Daniele Peluso
Livia Perfetto
Pablo Porras
Arathi Raghunath
Sylvie Ricard-Blum
Bernd Roechert
Andre Stutz
Michael Tognolli
Kim van Roey
Gianni Cesareni
Henning Hermjakob

Funding

British Heart Foundation RG/13/5/30112NHLBI NIH HHS HHSN268201000035CTelethon GGP09243
6 · The paper itself

Abstract

IntAct (freely available at http://www.ebi.ac.uk/intact) is an open-source, open data molecular interaction database populated by data either curated from the literature or from direct data depositions. IntAct has developed a sophisticated web-based curation tool, capable of supporting both IMEx- and MIMIx-level curation. This tool is now utilized by multiple additional curation teams, all of whom annotate data directly into the IntAct database. Members of the IntAct team supply appropriate levels of training, perform quality control on entries and take responsibility for long-term data maintenance. Recently, the MINT and IntAct databases decided to merge their separate efforts to make optimal use of limited developer resources and maximize the curation output. All data manually curated by the MINT curators have been moved into the IntAct database at EMBL-EBI and are merged with the existing IntAct dataset. Both IntAct and MINT are active contributors to the IMEx consortium (http://www.imexconsortium.org).

Indexed as

Databases, ProteinProtein Interaction MappingInternetSoftware

Identifiers

PMID24234451
PMCPMC3965093

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.