Evidence map›Paper›PMID 24233663›Full record

ReviewImmunologic research2013

Transdisciplinary approach to restore pancreatic islet function.

Carmen Fotino, R Damaris Molano, Camillo Ricordi, Antonello Pileggi

Abstract readReview
PubMed Publisher
In one paragraph

Review in Immunologic research, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Re-engineering islet cell transplantation.Pharmacological research · 2015
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Carmen Fotino
R Damaris Molano
Camillo Ricordi
Antonello Pileggi

Funding

Virginia Mason/UCHSC Autoimmune Prevention CenterU19AI050864 · NIAID · UNIVERSITY OF COLORADO DENVER · PI EISENBARTH, GEORGE S · 2001 to 2011
$29.2M
Strategies to Improve Long Term Islet Graft SurvivalU01DK070460 · NIDDK · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI RICORDI, CAMILLO · 2004 to 2012
$11.6M
ISLET CELL RESOURCE FOR DIABETES RESEARCH AND TREATMENTU42RR016603 · NCRR · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI RICORDI, CAMILLO · 2001 to 2009
$7.8M
PATHWAYS TO TOLERANCE IN HUMAN ISLET TRANSPLANTATIONR01DK056953 · NIDDK · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI RICORDI, CAMILLO · 2000 to 2004
$5.1M
Multi-Disciplinary Approaches to Driving Therapeutic Human Beta Cell ReplicationU01DK089538 · NIDDK · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI STEWART, ANDREW F. · 2010 to 2014
$3.6M
PANCREATIC TRANSPLANTATION AND DIABETIC MELLITUSR01DK025802 · NIDDK · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI INVERARDI, LUCA · 1986 to 2005
$2.5M
NCRR NIH HHS 5U42RR016603-08S1NIAID NIH HHS 5U19AI050864-10NIDDK NIH HHS 1U01DK70460-02NIDDK NIH HHS 5R01DK25802-24NIDDK NIH HHS 5R01DK56953-05NIDDK NIH HHS U01DK089538
6 · The paper itself

Abstract

The focus of our research is on islet immunobiology. We are exploring novel strategies that could be of assistance in the treatment and prevention of type 1 diabetes, as well as in the restoration of metabolic control via transplantation of insulin producing cells (i.e., islet cells). The multiple facets of diabetes and β-cell replacement encompass different complementary disciplines, such as immunology, cell biology, pharmacology, and bioengineering, among others. Through their interaction and integration, a transdisciplinary dimension is needed in order to address and overcome all aspects of the complex puzzle toward a successful clinical translation of a biological cure for diabetes.

Indexed as

Adenosine TriphosphateAnimalsCellular MicroenvironmentDiabetes Mellitus, Type 1HumansHyperbaric OxygenationInsulin-Secreting CellsIslets of LangerhansIslets of Langerhans TransplantationSignal TransductionAdenosine Triphosphate

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.