Evidence map›Paper›PMID 24232697›Full record

Observational studyThe European respiratory journal2014

Multidimensional approach to non-cystic fibrosis bronchiectasis: the FACED score.

Miguel Á Martínez-García, Javier de Gracia, Monserrat Vendrell Relat, Rosa-Maria Girón, Luis Máiz Carro, David de la Rosa Carrillo, Casilda Olveira

2 registry-linked trialsAbstract readMulticenter StudyObservational Study
PubMed Publisher
In one paragraph

Observational study in The European respiratory journal, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 224 papers, 8 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
224citing papers in PubMed, 8 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02507843 phase4unknown statusnot on this mapstarted 2015, after this paper: background citation

Vitamin D as an Adjunctive Treatment in Patients With Non-Cystic Fibrosis Bronchiectasis: a Double-blind Randomised Controlled Trial

TypeinterventionalSponsorShanghai Pulmonary Hospital, Shanghai, ChinaRan2015 to 2017Enrolled200ConditionsBronchiectasisArmsCholecalciferol, Placebo
NCT03262064 terminatednot on this mapstarted 2017, after this paper: background citation

Different Phenotypes of Bronchiectasis

TypeobservationalSponsorAssiut UniversityRan2017 to 2019Enrolled100ConditionsBronchiectasisArmsPulmonary function tests,Bronchiectasis severity index score
3 · Its place in the literature

Who cites it

224 citing papers in PubMed, 8 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Guideline
  4. Pooled it
  5. Pooled it
  6. Dual antibiotics for bronchiectasis.The Cochrane database of systematic reviews · 2018
    Pooled it
  7. Self-management for bronchiectasis.The Cochrane database of systematic reviews · 2018
    Pooled it
  8. Pooled it
  9. Autologous transplantation of P63Cell reports. Medicine · 2024
    Trial
  10. Trial
  11. Trial
  12. Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. Article
  20. Article

164 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Miguel Á Martínez-GarcíaHospital Universitario y Politécnico La Fe, Valencia.
Javier de Gracia
Monserrat Vendrell Relat
Rosa-Maria Girón
Luis Máiz Carro
David de la Rosa Carrillo
Casilda Olveira

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bronchiectasis is a multidimensional disease and, therefore, its severity or prognosis cannot be adequately quantified by analysing one single variable. The objective of the present study was to develop a multidimensional score that classifies the severity of bronchiectasis according to its prognosis. This is an observational multicentre study including 819 patients diagnosed with non-cystic fibrosis bronchiectasis using high-resolution computed tomography. 397 subjects were selected at random to construct the score while the remaining 422 were used for its validation. The outcome was 5-year all-cause mortality after radiological diagnosis. A logistic regression analysis was used to select the variables included in the final score. The final seven-point score incorporated five dichotomised variables: forced expiratory volume in 1 s % predicted (F, cut-off 50%, maximum value 2 points); age (A, cut-off 70 years, maximum value 2 points); presence of chronic colonisation by Pseudomonas aeruginosa (C, dichotomic, maximum value 1 point); radiological extension (E, number of lobes affected, cut-off two lobes, maximum value 1 point); and dyspnoea (D, cut-off grade II on the Medical Research Council scale, maximum value 1 point) to construct the FACED score. The validation cohort confirmed the score's validity. We conclude that this easy-to-use multidimensional grading system proved capable of accurately classifying the severity of bronchiectasis according to its prognosis.

Indexed as

AgedArea Under CurveBronchiectasisCohort StudiesFemaleFollow-Up StudiesForced Expiratory VolumeHumansKaplan-Meier EstimateMaleMiddle AgedPredictive Value of TestsPrognosisPulmonary MedicineRegression AnalysisSeverity of Illness Index

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.