ArticleGenetics in medicine : official journal of the American College of Medical Genetics2014
Economic analyses of genetic tests in personalized medicine: clinical utility first, then cost utility.
Article in Genetics in medicine : official journal of the American College of Medical Genetics, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04331535 (Pragmatic Randomized Trial of Polygenic Risk Scoring for Common Diseases in Primary Care), which is not on this map. Cited by 12 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Pragmatic Randomized Trial of Polygenic Risk Scoring for Common Diseases in Primary Care
Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Which BRCA genetic testing programs are ready for implementation in health care? A systematic review of economic evaluations.Genetics in medicine : official journal of the American College of Medical Genetics · 2016Pooled it
- The Impact of Whole-Genome Sequencing on the Primary Care and Outcomes of Healthy Adult Patients: A Pilot Randomized Trial.Annals of internal medicine · 2017Trial
- Application of Genomic Selection in Beef Cattle Disease Prevention.Animals : an open access journal from MDPI · 2025Review
- Pharmacogenomic testing in paediatrics: Clinical implementation strategies.British journal of clinical pharmacology · 2022Review
- A proposed approach to accelerate evidence generation for genomic-based technologies in the context of a learning health system.Genetics in medicine : official journal of the American College of Medical Genetics · 2018Review
- Epidemiology matters: peering inside the "black box" in economic evaluations of genetic testing.Genetics in medicine : official journal of the American College of Medical Genetics · 2016Article
- The Use of Economic Evaluation to Inform Newborn Screening Policy Decisions: The Washington State Experience.The Milbank quarterly · 2016Article
- Assessing the Costs and Cost-Effectiveness of Genomic Sequencing.Journal of personalized medicine · 2015Review
- When is Genomic Testing Cost-Effective? Testing for Lynch Syndrome in Patients with Newly-Diagnosed Colorectal Cancer and Their Relatives.Healthcare (Basel, Switzerland) · 2015Article
- Utility before business.Genetics in medicine : official journal of the American College of Medical Genetics · 2014Article
- Personalized Medicine's Bottleneck: Diagnostic Test Evidence and Reimbursement.Journal of personalized medicine · 2014Article
- 'Someday it will be the norm': physician perspectives on the utility of genome sequencing for patient care in the MedSeq Project.Personalized medicineArticle
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Authors and funding
1 author.
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Abstract
PubMed holds no abstract for this paper.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.