ArticleAnnals of botany2014
Peroxynitrite (ONOO-) is endogenously produced in arabidopsis peroxisomes and is overproduced under cadmium stress.
Article in Annals of botany, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers.
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Who cites it
51 citing papers in PubMed, 135 citations in OpenAlex.
- An ESIPT-AIE nanosensor for ONOOJournal of nanobiotechnology · 2026Article
- Integration of NO and HPlant communications · 2026Review
- Cellular nitro-oxidative burden and survival through regulated cell death in the plants.Protoplasma · 2025Review
- Exogenous Nitric Oxide Promotes the Growth and Cadmium Accumulation of Alfalfa (Plants (Basel, Switzerland) · 2025Article
- Peroxisomal-dependent signalling and dynamics modulate plant stress responses: reactive oxygen and nitrogen species as key molecules.Journal of experimental botany · 2025Review
- SlTrxh functions downstream of SlMYB86 and positively regulates nitrate stress tolerance via S-nitrosation in tomato seedling.Horticulture research · 2024Article
- Deciphering molecular regulation of reactive oxygen species (ROS) and reactive nitrogen species (RNS) signalling networks in Oryza genus amid environmental stress.Plant cell reports · 2024Review
- Soybean (International journal of molecular sciences · 2023Article
- HPlant, cell & environment · 2023Review
- Functions of nitric oxide-mediated post-translational modifications under abiotic stress.Frontiers in plant science · 2023Review
- Assay of Reactive Oxygen/Nitrogen Species (ROS/RNS) in Arabidopsis Peroxisomes Through Fluorescent Protein Containing a Type 1 Peroxisomal Targeting Signal (PTS1).Methods in molecular biology (Clifton, N.J.) · 2023Article
- Interactions of melatonin, reactive oxygen species, and nitric oxide during fruit ripening: an update and prospective view.Journal of experimental botany · 2022Review
- BR-Mediated ProteinInternational journal of molecular sciences · 2022Article
- The Role of Nitric Oxide Signaling in Plant Responses to Cadmium Stress.International journal of molecular sciences · 2022Review
- Brassinosteroids Mitigate Cadmium Effects in Arabidopsis Root System without Any Cooperation with Nitric Oxide.International journal of molecular sciences · 2022Article
- Peroxisomal Proteome Mining of Sweet Pepper (Frontiers in plant science · 2022Article
- Response to Antimony Toxicity inAntioxidants (Basel, Switzerland) · 2021Article
- Peroxisomal PEX7 Receptor Affects Cadmium-Induced ROS and Auxin Homeostasis in Arabidopsis Root System.Antioxidants (Basel, Switzerland) · 2021Article
- Molecular Mechanisms of Nitric Oxide (NO) Signaling and Reactive Oxygen Species (ROS) Homeostasis during Abiotic Stresses in Plants.International journal of molecular sciences · 2021Review
- Peroxisomes as redox-signaling nodes in intracellular communication and stress responses.Plant physiology · 2021Review
Corrections and comments
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Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND AND
aimsPeroxisomes are subcellular compartments involved in multiple cellular metabolic pathways. Peroxynitrite (ONOO(-)) is a nitric oxide-derived molecule which is a nitrating species that causes nitration of proteins. This study used cell biology techniques to explore the potential presence of peroxynitrite in peroxisomes and evaluated its content under stress conditions (excess cadmium).
methodsPeroxynitrite, nitric oxide and superoxide anion were studied using cell-permeable specific fluorescent probes by confocal laser scanning microscopy in Arabidopsis thaliana transgenic plants expressing cyan fluorescent protein through the addition of peroxisomal targeting signal 1 (PTS1), which enables peroxisomes to be visualized in vivo. Key Results When no stress was applied, peroxynitrite was clearly localized in the peroxisomes of roots and stomatal guard cells. Under cadmium (150 μm) stress, the generation of peroxynitrite, nitric oxide and the superoxide anion (O2(·-)) increased and was localized in peroxisomes and the cytosol, participating in the generation of nitro-oxidative stress.
conclusionsThe results show that peroxisomes are an endogenous source of peroxynitrite, which is over-produced under cadmium stress, suggesting that the metabolism of reactive nitrogen species in peroxisomes could participate in the mechanism of the response to this heavy metal.
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