Trial reportSurgical endoscopy2014
Endoscopic submucosal dissection versus transanal endoscopic microsurgery for the treatment of early rectal cancer.
Trial report in Surgical endoscopy, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 11 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
35 citing papers in PubMed, 11 syntheses or guidelines pooled it, 80 citations in OpenAlex.
- Endoscopic resection versus surgery for T1 rectal cancer: A systematic review and meta-analysis of oncologic and safety outcomes.Surgical endoscopy · 2026Pooled it
- The Korean Rectal Cancer Multidisciplinary Committee Clinical Practice Guidelines for Rectal Cancer version 2.0.Annals of coloproctology · 2026Guideline
- Comparison of endoscopic submucosal dissection and transanal endoscopic surgery for the treatment of rectal neoplasia: A systematic review and meta-analysis.Clinics (Sao Paulo, Brazil) · 2025Pooled it
- Endoscopic and trans-anal local excision vs. radical resection in the treatment of early rectal cancer: A systematic review and network meta-analysis.International journal of colorectal disease · 2023Pooled it
- Surgical, oncological, and functional outcomes of local and radical resection after neoadjuvant chemotherapy or chemoradiotherapy for early- and mid-stage rectal cancer: a systematic review and meta-analysis.International journal of colorectal disease · 2023Pooled it
- Transanal endoscopic microsurgery versus radical resection for early-stage rectal cancer: a systematic review and meta- analysis.International journal of colorectal disease · 2023Pooled it
- Endoscopic management versus transanal surgery for early primary or early locally recurrent rectal neoplasms-a systematic review and meta-analysis.International journal of colorectal disease · 2020Pooled it
- Endoscopic submucosal dissection versus transanal endoscopic surgery for the treatment of early rectal tumor: a systematic review and meta-analysis.Surgical endoscopy · 2020Pooled it
- Colonoscopy Surveillance after Colorectal Cancer Resection: Recommendations of the US Multi-Society Task Force on Colorectal Cancer.The American journal of gastroenterology · 2016Guideline
- Endoscopic submucosal dissection versus local excision for early rectal cancer: a systematic review and meta-analysis.Techniques in coloproctology · 2016Pooled it
- Early rectal cancer: the European Association for Endoscopic Surgery (EAES) clinical consensus conference.Surgical endoscopy · 2015Guideline
- Efficacy, Safety and Oncological Outcomes of Minimally Invasive Approaches (EMR, ESD and TAMIS) for Early Rectal Tumors: A Systematic Review and Meta-Analysis.Medical devices (Auckland, N.Z.) · 2026Review
- Case Report: Rare case of primary rectal adenocarcinoma presenting as a smooth submucosal elevation: endoscopic submucosal excavation and 4 years and 11 months follow-up.Frontiers in medicine · 2026Article
- Meta-analysis of clinical efficacy and safety of transanal endoscopic microsurgery and endoscopic submucosal dissection in the treatment of rectal tumors.Wideochirurgia i inne techniki maloinwazyjne = Videosurgery and other miniinvasive techniques · 2024Article
- Endoscopic submucosal dissectionWorld journal of clinical cases · 2024Article
- The Role of Transanal Endoscopic Surgery for Early Rectal Cancer.Clinics in colon and rectal surgery · 2022Review
- Two-step ESD: an option for en-bloc resection of extensive colorectal laterally spreading tumors.Endoscopy international open · 2019Article
- Feasibility of endoscopic submucosal dissection of lesions at anastomosis site post-colorectal surgery: a case series.Endoscopy international open · 2019Article
- Colorectal endoscopic submucosal dissection in special locations.World journal of gastrointestinal endoscopy · 2019Review
- Management of complex polyps of the colon and rectum.International journal of colorectal disease · 2018Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundEndoscopic submucosal dissection (ESD) and transanal endoscopic microsurgery (TEM) are minimally invasive procedures that can be used to treat early rectal cancer.
objectiveThe aim of this study was to compare clinical efficacy between ESD and TEM for the treatment of early rectal cancer.
methodsBetween July 2008 and August 2011, 24 patients with early rectal cancers were treated by ESD (11) or TEM (13) at the Cancer Institute of São Paulo University Medical School (São Paulo, Brazil). Data were analyzed retrospectively according to database and pathological reports, with respect to en bloc resection rate, local recurrence, complications, histological diagnosis, procedure time and length of hospital stay.
resultsEn bloc resection rates with free margins were achieved in 81.8 % of patients in the ESD group and 84.6 % of patients in the TEM group (p = 0.40). Mean tumor size was 64.6 ± 57.9 mm in the ESD group and 43.9 ± 30.7 mm in the TEM group (p = 0.13). Two patients in the TEM group and one patient in the ESD group had a local recurrence. The mean procedure time was 133 ± 94.8 min in the ESD group and 150 ± 66.3 min in the TEM group (p = 0.69). Mean hospital stay was 3.8 ± 3.3 days in the ESD group and 4.08 ± 1.7 days in the TEM group (p = 0.81). LIMITATIONS: This was a non-randomized clinical trial with a small sample size and selection bias in treatment options.
conclusionESD and TEM are both safe and effective for the treatment of early rectal cancer.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.