Evidence map›Paper›PMID 24231853›Full record

ArticleAJNR. American journal of neuroradiology2014

Temporal correlation between wall shear stress and in-stent stenosis after Wingspan stent in swine model.

M Fujimoto, H Takao, T Suzuki, Y Shobayashi, F Mayor, S Tateshima, M Yamamoto, Y Murayama, F Viñuela

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in AJNR. American journal of neuroradiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact, top 82% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Review
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  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

M FujimotoFrom the Division of Interventional Neuroradiology (M.F., H.T., Y.S., F.M., S.T., Y.M., F.V.), Department of Radiological Sciences, David Geffen School of Medicine, University of California, Los Angeles, California moto.fujimo@gmail.com.
H TakaoFrom the Division of Interventional Neuroradiology (M.F., H.T., Y.S., F.M., S.T., Y.M., F.V.), Department of Radiological Sciences, David Geffen School of Medicine, University of California, Los Angeles, CaliforniaDepartment of Neurosurgery (H.T., T.S., Y.M.), Jikei University School of Medicine, Tokyo, Japan.
T SuzukiDepartment of Neurosurgery (H.T., T.S., Y.M.), Jikei University School of Medicine, Tokyo, JapanDepartment of Mechanical Engineering (T.S., M.Y.), Graduate School of Engineering, Tokyo University of Science, Tokyo, Japan.
Y ShobayashiFrom the Division of Interventional Neuroradiology (M.F., H.T., Y.S., F.M., S.T., Y.M., F.V.), Department of Radiological Sciences, David Geffen School of Medicine, University of California, Los Angeles, California.
F MayorFrom the Division of Interventional Neuroradiology (M.F., H.T., Y.S., F.M., S.T., Y.M., F.V.), Department of Radiological Sciences, David Geffen School of Medicine, University of California, Los Angeles, California.
S TateshimaFrom the Division of Interventional Neuroradiology (M.F., H.T., Y.S., F.M., S.T., Y.M., F.V.), Department of Radiological Sciences, David Geffen School of Medicine, University of California, Los Angeles, California.
M YamamotoDepartment of Mechanical Engineering (T.S., M.Y.), Graduate School of Engineering, Tokyo University of Science, Tokyo, Japan.
Y MurayamaFrom the Division of Interventional Neuroradiology (M.F., H.T., Y.S., F.M., S.T., Y.M., F.V.), Department of Radiological Sciences, David Geffen School of Medicine, University of California, Los Angeles, CaliforniaDepartment of Neurosurgery (H.T., T.S., Y.M.), Jikei University School of Medicine, Tokyo, Japan.
F ViñuelaFrom the Division of Interventional Neuroradiology (M.F., H.T., Y.S., F.M., S.T., Y.M., F.V.), Department of Radiological Sciences, David Geffen School of Medicine, University of California, Los Angeles, California.
University of California, Los Angeles · USJikei University School of Medicine · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background and purposeA recent randomized clinical trial on intracranial atherosclerosis was discontinued because of the higher frequency of stroke and death in the angioplasty and stent placement group than in the medical treatment group. An in-depth understanding of the relationship between biologic responses and flow dynamics is still required to identify the current limitations of intracranial stent placement. MATERIALS AND

methodsFive Wingspan stents were deployed in tapered swine ascending pharyngeal arteries. Temporal wall shear stress distributions and in-stent stenosis were evaluated at days 0, 7, 14, and 28 after stent placement. The physiologic role of wall shear stress was analyzed regarding its correlation with in-stent stenosis.

resultsIn-stent stenosis reached a peak of nearly 40% at day 14 and decreased mainly at the distal stent segment until day 28. The wall shear stress demonstrated a characteristic pattern with time on the basis of the in-stent stenosis change. The wall shear stress gradient increased from the proximal to distal segment until day 14. At day 28, the trend was reversed dramatically, decreasing from the proximal to the distal segment. A significant correlation between the in-stent stenosis growth until day 14 and low wall shear stress values just after stent placement was detected. In-stent stenosis regression between days 14 and 28 was also associated with the high wall shear stress values at day 14.

conclusionsThese data suggest that the physiologic wall shear stress can control the biphasic in-stent stenosis change in tapered arteries.

Indexed as

AgingAnimalsArteriesBlood Flow VelocityBlood PressureBlood Vessel ProsthesisComputer SimulationDisease Models, AnimalEquipment Failure AnalysisGraft Occlusion, VascularModels, CardiovascularProsthesis DesignShear StrengthStentsStress, MechanicalSwine

Identifiers

PMID24231853
PMCPMC7964559
OpenAlexW2136347070

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.