ArticleNanotechnology2013
Surface modification of graphene nanopores for protein translocation.
Article in Nanotechnology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 63 citations in OpenAlex.
- Heterogeneous Multilayer Nanopores via Chemically Tuned Dielectric Breakdown for Single-Molecule Sensing.Small (Weinheim an der Bergstrasse, Germany) · 2026Article
- Electrostatic-driven dehydration of ions in nanoporous membranes.Science advances · 2025Article
- Graphene Nanopore Fabrication and Applications.International journal of molecular sciences · 2025Review
- Fluids and Electrolytes under Confinement in Single-Digit Nanopores.Chemical reviews · 2023Review
- Multifunctional graphene heterogeneous nanochannel with voltage-tunable ion selectivity.Nature communications · 2022Article
- Sensing with Nanopores and Aptamers: A Way Forward.Sensors (Basel, Switzerland) · 2020Review
- Step-defect guided delivery of DNA to a graphene nanopore.Nature nanotechnology · 2019Article
- Colloquium: Ionic phenomena in nanoscale pores through 2D materials.Reviews of modern physics · 2019Article
- A graphene aptasensor for biomarker detection in human serum.Electrochimica acta · 2018Article
- Hydrogen Peroxide Sensing Based on Inner Surfaces Modification of Solid-State Nanopore.Nanoscale research letters · 2017Article
- Single-layer MoS2 nanopores as nanopower generators.Nature · 2016Article
- Graphene Nanopores for Protein Sequencing.Advanced functional materials · 2016Article
- Ion selectivity of graphene nanopores.Nature communications · 2016Article
- Selectively Sized Graphene-Based Nanopores for in Situ Single Molecule Sensing.ACS applied materials & interfaces · 2015Article
- A surface plasmon resonance study of the intermolecular interaction between Escherichia coli topoisomerase I and pBAD/Thio supercoiled plasmid DNA.Biochemical and biophysical research communications · 2014Article
Corrections and comments
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Authors and funding
11 authors at 5 institutions in 2 countries.
Funding
Abstract
Studies of DNA translocation through graphene nanopores have revealed their potential for DNA sequencing. Here we report a study of protein translocation through chemically modified graphene nanopores. A transmission electron microscope (TEM) was used to cut nanopores with diameters between 5 and 20 nm in multilayer graphene prepared by chemical vapor deposition (CVD). After oxygen plasma treatment, the dependence of the measured ionic current on salt concentration and pH was consistent with a small surface charge induced by the formation of carboxyl groups. While translocation of gold nanoparticles (10 nm) was readily detected through such treated pores of a larger diameter, translocation of the protein ferritin was not observed either for oxygen plasma treated pores, or for pores modified with mercaptohexadecanoic acid. Ferritin translocation events were reliably observed after the pores were modified with the phospholipid-PEG (DPPE-PEG750) amphiphile. The ion current signature of translocation events was complex, suggesting that a series of interactions between the protein and pores occurs during the process.
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