Trial reportChild and adolescent psychiatric clinics of North America2014
Examination of aggression and self-injury in children with autism spectrum disorders and serious behavioral problems.
Trial report in Child and adolescent psychiatric clinics of North America, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03432832 (Emotion Awareness and Skills Enhancement), which is not on this map. Cited by 24 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Emotion Awareness and Skills Enhancement (EASE) Program: A Clinical Trial
Who cites it
24 citing papers in PubMed, 1 synthesis or guideline pooled it, 71 citations in OpenAlex.
- [Early death and causes of death of patients with autism spectrum disorders: A systematic review].Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences · 2023Pooled it
- Using a Patient-Centered Outcome Measure to Test Methylphenidate Versus Placebo in Children with Autism Spectrum Disorder.Journal of child and adolescent psychopharmacology · 2017Trial
- Lurasidone for the Treatment of Irritability Associated with Autistic Disorder.Journal of autism and developmental disorders · 2016Trial
- High-Dose Propranolol for Severe and Chronic Aggression in Autism Spectrum Disorder: A Pilot, Double-Blind, Placebo-Controlled, Randomized Crossover Study.Journal of clinical psychopharmacologyTrial
- Systematic Review of the Efficacy of Parent-Mediated Interventions in Reducing Problem Behaviours Shown by Autistic Adolescents.Journal of autism and developmental disorders · 2026Article
- Experiences of siblings of individuals with autism spectrum disorders.International journal of developmental disabilities · 2025Article
- Probing heterogeneity to identify individualized treatment approaches in autism: Specific clusters of executive function challenges link to distinct co-occurring mental health problems.Autism : the international journal of research and practice · 2024Article
- Video-based interventions promoting social behavioural skills for autistic children and young people: An evidence and gap map.Campbell systematic reviews · 2024Article
- Early Childhood Aggression in Autistic and Non-Autistic Preschoolers: Prevalence, Topography, and Relationship to Emotional Reactivity.JAACAP open · 2024Article
- Discordance Between Psychiatric Diagnoses and Medication Use in Children and Adults With Autism Presenting in Crisis.Focus (American Psychiatric Publishing) · 2024Article
- Drug-refractory irritability and related factors in autistic children.International journal of developmental disabilities · 2024Article
- Exploring factors of successful transition to elementary school among children with autism spectrum disorder in Japan: a focus group study.International journal of developmental disabilities · 2024Article
- Development and Psychometric Evaluation of the Open-Source Challenging Behavior Scale (OS-CBS).Journal of autism and developmental disorders · 2023Article
- Maladaptive Aggression: With a Focus on Impulsive Aggression in Children and Adolescents.Journal of child and adolescent psychopharmacology · 2019Review
- Management of Self-injurious Behaviors in Children with Neurodevelopmental Disorders: A Pharmacotherapy Overview.Pharmacotherapy · 2019Review
- Self-injurious behaviors in children with autism spectrum disorder enrolled in the Study to Explore Early Development.Autism : the international journal of research and practice · 2018Article
- Characteristics of unintentional drowning deaths in children with autism spectrum disorder.Injury epidemiology · 2017Article
- Injury Mortality in Individuals With Autism.American journal of public health · 2017Article
- Relationship between brain stem volume and aggression in children diagnosed with autism spectrum disorder.Research in autism spectrum disorders · 2017Article
- Factors Associated with Self-Injurious Behaviors in Children with Autism Spectrum Disorder: Findings from Two Large National Samples.Journal of autism and developmental disorders · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
15 authors at 11 institutions in 2 countries.
Funding
Abstract
This study identified subtypes of aggression in a sample of 206 children with autism spectrum disorder (ASD) who participated in 2 risperidone trials. The narratives were derived from a parent interview about each child's 2 most pressing problems. Five subtypes of aggression emerged: hot aggression only, cold aggression only, self-injurious behavior (SIB) only, aggression and SIB, and nonaggressive. All groups showed a high rate of positive response to risperidone with no differences across subtypes. These study findings extend understanding of aggression in ASD and may be useful to guide further study on biological mechanisms and individualized treatment in ASD.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.