Trial reportScandinavian journal of primary health care2013
Acupuncture for infantile colic: a blinding-validated, randomized controlled multicentre trial in general practice.
Trial report in Scandinavian journal of primary health care, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 4 registered trials, which are not on this map. Cited by 22 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effects of Acupuncture in the Treatment of Infant Colic: A Prospective Multi-center Single Blinded Randomized Controlled Study
The Effects of Visceral Manual Therapy on Infant Colic Symptoms. A Controlled Clinical Trial
Effectiveness of Manual Therapy Through Osteopathy in the Treatment of Infant Colic.
Acupuncture in Infantile Colic - A Randomised Trial.
Who cites it
22 citing papers in PubMed, 4 syntheses or guidelines pooled it, 46 citations in OpenAlex.
- Parent training programmes for managing infantile colic.The Cochrane database of systematic reviews · 2019Pooled it
- Acupuncture treatments for infantile colic: a systematic review and individual patient data meta-analysis of blinding test validated randomised controlled trials.Scandinavian journal of primary health care · 2018Pooled it
- Efficacy of Lactobacillus reuteri DSM 17938 for infantile colic: Systematic review with network meta-analysis.Medicine · 2017Pooled it
- Pooled it
- Effect of minimal acupuncture for infantile colic: a multicentre, three-armed, single-blind, randomised controlled trial (ACU-COL).Acupuncture in medicine : journal of the British Medical Acupuncture Society · 2017Trial
- Standardized minimal acupuncture, individualized acupuncture, and no acupuncture for infantile colic: study protocol for a multicenter randomized controlled trial - ACU-COL.BMC complementary and alternative medicine · 2015Trial
- Acupuncture for the treatment of infantile colic.The Cochrane database of systematic reviews · 2025Article
- How Do Mothers Take Care of Their Infants with Colic Pain? A Mixed-Method Study.Ethiopian journal of health sciences · 2021Article
- Acupuncture for pediatric pain: The trend of evidence-based research.Journal of traditional and complementary medicine · 2020Review
- Complementary and alternative medicine experiences of mothers in the treatment of infantile colic.Sudanese journal of paediatrics · 2020Article
- An overview of systematic reviews of complementary and alternative therapies for infantile colic.Systematic reviews · 2019Review
- A Scoping Review of Acupuncture as a Potential Intervention for Neonatal Abstinence Syndrome.Medical acupuncture · 2019Article
- Infantile Colic: New Insights into an Old Problem.Gastroenterology clinics of North America · 2018Review
- Infant colic: mechanisms and management.Nature reviews. Gastroenterology & hepatology · 2018Review
- Use of Acupuncture in an Infant with Restlessness and Agitation.Medicines (Basel, Switzerland) · 2018Article
- Acupuncture for Infantile Colic: A Systematic Review of Randomised Controlled Trials.Evidence-based complementary and alternative medicine : eCAM · 2018Review
- 'Big needles, small bodies'-the absence of acupuncture treatment for infants in contemporary Shanghai: a qualitative study.BMJ open · 2015Article
- Acupuncture in the treatment of infantile colic.Italian journal of pediatrics · 2015Article
- Changes of locoregional skin temperature in neonates undergoing laser needle acupuncture at the acupuncture point large intestine 4.Evidence-based complementary and alternative medicine : eCAM · 2015Article
- Looking for new treatments of Infantile Colic.Italian journal of pediatrics · 2014Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveInfantile colic is a painful condition in the first months of infancy. Acupuncture is used in Scandinavia as a treatment for infantile colic. A randomized controlled trial was carried out with the aim of testing the hypothesis that acupuncture treatment has a clinically relevant effect for this condition.
designA prospective, blinding-validated, randomized controlled multicentre trial in general practice. Research assistants and parents were blinded.
setting13 GPs' offices in Southern Norway.
interventionThree days of bilateral needling of the acupuncture point ST36, with no treatment as control. SUBJECTS: 113 patients were recruited; 23 patients were excluded, and 90 randomized; 79 diaries and 84 interviews were analysed.
main outcome measuresDifference in changes in crying time during the trial period between the intervention and control group.
resultsThe blinding validation questions showed a random distribution with p = 0.41 and 0.60, indicating true blinding. We found no statistically significant difference in crying time reduction between acupuncture and control group at any of the measured intervals, nor in the main analysis of differences in changes over time (p = 0.26). There was a tendency in favour of the acupuncture group, with a non-significant total baseline-corrected mean of 13 minutes (95% CI -24 to + 51) difference in crying time between the groups. This was not considered clinically relevant, according to protocol.
conclusionThis trial of acupuncture treatment for infantile colic showed no statistically significant or clinically relevant effect. With the current evidence, the authors suggest that acupuncture for infantile colic should be restricted to clinical trials.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.