ArticleKorean journal of orthodontics2013
Orthodontic and surgical management of cleidocranial dysplasia.
Article in Korean journal of orthodontics, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 41 citations in OpenAlex.
- Correlation of RUNX2 Variants With Craniofacial-Dental Phenotypes in Cleidocranial Dysplasia.Clinical and experimental dental research · 2026Article
- The Impact of Genetics on Craniofacial Dysplasias and Consequent Oral Malformations-Integrative Review.Genes · 2026Review
- Cleidocranial dysplasia with preserved function under conservative management: a case report.Frontiers in pediatrics · 2026Article
- Review
- Cleidocranial dysplasia: a case report and gene mutation analysis.Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology · 2022Article
- Appropriateness of standard cephalometric norms for the assessment of dentofacial characteristics in patients with cleidocranial dysplasia.Dento maxillo facial radiology · 2022Article
- Combined surgical-orthodontic treatment of patients with cleidocranial dysplasia: case report and review of the literature.Orphanet journal of rare diseases · 2018Review
- Characterization of dental phenotype in patients with cleidocranial dysplasia using longitudinal data.The Angle orthodontist · 2018Article
- Surgical Management and Evaluation of the Craniofacial Growth and Morphology in Cleidocranial Dysplasia.The Journal of craniofacial surgery · 2018Article
- Delayed Eruption of Permanent Dentition and Maxillary Contraction in Patients with Cleidocranial Dysplasia: Review and Report of a Family.International journal of dentistry · 2018Review
- Cleidocranial Dysplasia-dental Disorder Treatment and Audiology Diagnosis.Open medicine (Warsaw, Poland) · 2018Article
- Complex dental anomalies in a belatedly diagnosed cleidocranial dysplasia patient.Imaging science in dentistry · 2015Article
- Combined surgical-orthodontic rehabilitation of cleidocranial dysplasia: 5 years follow-up.World journal of clinical cases · 2015Article
- Histological examination and clinical evaluation of the jawbone of an adult patient with cleidocranial dysplasia: a case report.International journal of clinical and experimental pathology · 2015Article
- Systemic treatment with strontium ranelate accelerates the filling of a bone defect and improves the material level properties of the healing bone.BioMed research international · 2014Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cleidocranial dysplasia (CCD), an autosomal dominant disorder with a prevalence of 1 in 1,000,000 individuals, is mainly caused by mutations in Runx2, a gene required for osteoblastic differentiation. It is generally characterized by hypoplastic clavicles, narrow thorax, and delayed or absent fontanel closure. Importantly, its orofacial manifestations, including midfacial hypoplasia, retained primary teeth, and impacted permanent and supernumerary teeth, severely impede the well-being of affected individuals. Successful treatment of the orofacial problems requires the combined efforts of dental specialists. However, only a few successfully treated cases have been reported because of the rarity of CCD and complexity of the treatment. This article presents the University of California, San Francisco (UCSF) treatment protocol for the dentofacial manifestations of CCD based on two treated and 17 diagnosed cases. The records of two patients with CCD who had been treated at the UCSF School of Dentistry and the treatment options reported in the literature were reviewed. The UCSF treatment protocol produced a successful case and a partially successful one (inadequate oral hygiene in the retention stage resulted in decay and loss of teeth). It provides general guidelines for successfully treating the orofacial manifestations of CCD.
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