ReviewAdvances in nutrition (Bethesda, Md.)2013
The metabolic and endocrine response and health implications of consuming sugar-sweetened beverages: findings from recent randomized controlled trials.
Review in Advances in nutrition (Bethesda, Md.), 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 14 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 43 citations in OpenAlex.
- Trial
- Trial
- Elucidating neural molecular mechanisms underlying metabolic disorders-induced neuropsychiatric disorders in mice on prolonged high fructose diet.Metabolic brain disease · 2025Article
- A higher Mediterranean diet adherence and exercise practice are associated with a healthier drinking profile in a healthy Spanish adult population.European journal of nutrition · 2017Article
- Relationship between Added Sugars Consumption and Chronic Disease Risk Factors: Current Understanding.Nutrients · 2016Review
- Article
- Added sugars and risk factors for obesity, diabetes and heart disease.International journal of obesity (2005) · 2016Review
- Sweeteners and health: findings from recent research and their impact on obesity and related metabolic conditions.International journal of obesity (2005) · 2016Review
- Fructose-containing sugars and cardiovascular disease.Advances in nutrition (Bethesda, Md.) · 2015Review
- Fructose consumption in the Netherlands: the Dutch National Food Consumption Survey 2007-2010.European journal of clinical nutrition · 2015Article
- Compared to sucrose, previous consumption of fructose and glucose monosaccharides reduces survival and fitness of female mice.The Journal of nutrition · 2015Article
- Fructose Metabolism and Relation to Atherosclerosis, Type 2 Diabetes, and Obesity.Journal of nutrition and metabolism · 2015Review
- Opportunities for intervention strategies for weight management: global actions on fluid intake patterns.Obesity facts · 2015Review
- Breakfast consumption is positively associated with nutrient adequacy in Canadian children and adolescents.The British journal of nutrition · 2014Article
Corrections and comments
- Erratum issued
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Fructose-containing sugars, including fructose itself, high fructose corn syrup (HFCS), and sucrose have engendered considerable controversy. The effects of HFCS and sucrose in sugar-sweetened beverages, in particular, have generated intense scientific debate that has spilled over to the public. This controversy is related to well-known differences in metabolism between fructose and glucose in the liver. In addition, research studies have often been conducted comparing pure fructose and pure glucose even though neither is consumed to any appreciable degree in isolation in the human diet. Other evidence has been drawn from animal studies and epidemiologic or cohort studies. Few randomized controlled trials (RCTs) have compared HFCS with sucrose (the 2 sugars most commonly consumed in the human diet) at dosage amounts within the normal human consumption range. This review compares results of recently concluded RCTs with other forms of evidence related to fructose, HFCS, and sucrose. We conclude that great caution must be used when suggesting adverse health effects of consuming these sugars in the normal way they are consumed and at the normal amounts in the human diet, because RCTs do not support adverse health consequences at these doses when employing these sugars.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.