Evidence map›Paper›PMID 24228119›Full record

ArticleInternational journal of clinical and experimental pathology2013

CTLA-4 gene polymorphisms and susceptibility to chronic obstructive pulmonary disease.

Lijing Deng, Haixia Zhou, Jing Yang, Jun Xiao, Bo Wang, Lan Wang, Xuemei Ou, Yulin Feng

Open access · greenAbstract read
In one paragraph

Article in International journal of clinical and experimental pathology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Influence of molecular genetics in Vogt-Koyanagi-Harada disease.Journal of ophthalmic inflammation and infection · 2014
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Lijing DengDepartment of Intensive Care Unit, West China Hospital, Sichuan University Chengdu, Sichuan Province, China.
Haixia Zhou
Jing Yang
Jun Xiao
Bo Wang
Lan Wang
Xuemei Ou
Yulin Feng
Sichuan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe aim of this study was to investigate whether four single nucleotide polymorphisms (SNPs) in CTLA-4 gene are associated with chronic obstructive pulmonary disease (COPD) in a Chinese population.

methodsSamples were collected from a Chinese population and analyzed for the association of SNPs in CTLA-4 gene with COPD in a case-control study. Four SNPs (rs231775, rs3087243, rs231725, rs5742909) in CTLA-4 gene were chosen and genotyped. The results were then analyzed using statistical methods.

resultsWe found that none of these four SNPs (rs231775, rs3087243, rs231725, rs5742909) in CTLA-4 gene were associated with the disease.

conclusionOur data suggested that there was no significant association between these four SNPs in CTLA-4 gene and COPD susceptibility in a Chinese population.

Indexed as

Polymorphism, Single NucleotideAgedCase-Control StudiesChinaCTLA-4 AntigenFemaleForced Expiratory VolumeGene FrequencyGenetic Predisposition to DiseaseHumansLungMaleMiddle AgedModels, StatisticalPhenotypePulmonary Disease, Chronic ObstructiveCTLA-4 AntigenCTLA4 protein, humanchronic obstructive pulmonary diseaseCTLA-4polymorphisms

Identifiers

PMID24228119
PMCPMC3816826
OpenAlexW1769166611

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.