ArticleInternational journal of clinical and experimental pathology2013
The effect of porcine ADM to improve the burn wound healing.
Article in International journal of clinical and experimental pathology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it.
- [Meta-analysis of the effects of xenogeneic acellular dermal matrix dressings in the treatment of wounds in burn patients].Zhonghua shao shang yu chuang mian xiu fu za zhi · 2023Pooled it
- The use of acellular porcine dermis, hyaluronic acid and polynucleotides in the treatment of cutaneous ulcers: Single blind randomised clinical trial.International wound journal · 2020Trial
- The Effects and Molecular Mechanisms of a Peptide fromMolecules (Basel, Switzerland) · 2026Article
- Decellularized Extracellular Matrices for Skin Wound Treatment.Materials (Basel, Switzerland) · 2025Review
- Porcine Acellular Dermal Matrix Increases Fat Survival Rate after Fat Grafting in Nude Mice.Aesthetic plastic surgery · 2021Article
- Use of ovine acellular peritoneal matrix combined with honey and ovine fetal skin extract in the healing of full-thickness infected burn wounds in a rat model.Veterinary research forum : an international quarterly journal · 2020Article
- Effects of porcine acellular dermal matrix treatment on wound healing and scar formation: Role of Jag1 expression in epidermal stem cells.Organogenesis · 2018Article
- Marine Collagen Peptides from the Skin of Nile Tilapia (Oreochromis niloticus): Characterization and Wound Healing Evaluation.Marine drugs · 2017Article
- Use of Ozone to Treat Ileostomy Dermatitis in an Experimental Rat Model.Medical science monitor : international medical journal of experimental and clinical research · 2016Article
- A novel dermal matrix generated from burned skin as a promising substitute for deep-degree burns therapy.Molecular medicine reports · 2016Article
- The Use of Stem Cells in Burn Wound Healing: A Review.BioMed research international · 2015Review
- Article
Corrections and comments
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Authors and funding
13 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
To study the effect of porcine acellular dermal matrix (ADM) on the burn wound healing. Seventy healthy Wistar rats were inflicted with 2 cm second degree burn and divided into 2 groups; one group was treated with porcine ADM and the other with Povidone Iodine Cream. Biopsies were taken on day 1, 3, 5, 7, 10, 14, 21 for histopathological and biochemical analysis to test PCNA, K19, Integrin-β1, PDGF, EGF and FGF. The results revealed relatively better and faster regeneration after treatment of porcine ADM, along with greatly increased synthesis in collagen in the experimental group. PCNA, K19, Integrin-β1 had an increase and then tapered down, and were stronger in the experimental group than in the contrast group during 21 days after burns. PDGF, EGF and FGF levels increased on day 3, peaked on day 5 and then started to decrease, while significantly enhanced expression of relevant growth factors were observed in the experimental group. Porcine ADM stimulate collagen synthesis, stem cells proliferation and differentiation, and the expression of relevant growth factors and ultimately improve the burn wound healing.
Indexed as
Identifiers
24228089PMC3816796What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.