ReviewInternational journal of endocrinology2013
The Endocannabinoid System in the Postimplantation Period: A Role during Decidualization and Placentation.
Review in International journal of endocrinology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 46 citations in OpenAlex.
- Recreational Cannabis Use During Human Pregnancy: Its Effects on the Placenta and Endocannabinoid System.International journal of molecular sciences · 2026Review
- The First "Hit" to the Endocannabinoid System? Associations Between Prenatal Cannabis Exposure and Frontolimbic White Matter Pathways in Children.Biological psychiatry global open science · 2024Article
- Emerging Roles of Endocannabinoids as Key Lipid Mediators for a Successful Pregnancy.International journal of molecular sciences · 2023Review
- Effects of Prenatal Cannabinoids Exposure upon Placenta and Development of Respiratory Neural Circuits.Advances in experimental medicine and biology · 2023Review
- Cannabis and Cannabinoids in Reproduction and Fertility: Where We Stand.Reproductive sciences (Thousand Oaks, Calif.) · 2022Review
- Cannabis significantly alters DNA methylation of the human ovarian follicle in a concentration-dependent manner.Molecular human reproduction · 2022Article
- Article
- Metabolic Consequences of Gestational Cannabinoid Exposure.International journal of molecular sciences · 2021Review
- Cannabis alters epigenetic integrity and endocannabinoid signalling in the human follicular niche.Human reproduction (Oxford, England) · 2021Article
- Review
- Article
- The use of cannabis and perceptions of its effect on fertility among infertility patients.Human reproduction open · 2020Article
- Chinese Herbal Medicine (MaZiRenWan) Improves Bowel Movement in Functional Constipation Through Down-Regulating Oleamide.Frontiers in pharmacology · 2019Article
- Current model systems for the study of preeclampsia.Experimental biology and medicine (Maywood, N.J.) · 2018Review
- Marijuana, the Endocannabinoid System and the Female Reproductive System.The Yale journal of biology and medicine · 2016Review
- The Histochemistry and Cell Biology omnium-gatherum: the year 2015 in review.Histochemistry and cell biology · 2016Review
- A role for GPR55 in human placental venous endothelial cells.Histochemistry and cell biology · 2015Article
- Decreased circulating anandamide levels in preeclampsia.Hypertension research : official journal of the Japanese Society of Hypertension · 2015Article
- Increased placental expression of cannabinoid receptor 1 in preeclampsia: an observational study.BMC pregnancy and childbirth · 2014Observational
- It's not your mother's marijuana: effects on maternal-fetal health and the developing child.Clinics in perinatology · 2014Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Although the detrimental effects of cannabis consumption during gestation are known for years, the vast majority of studies established a link between cannabis consumption and foetal development. The complex maternal-foetal interrelationships within the placental bed are essential for normal pregnancy, and decidua definitively contributes to the success of this process. Nevertheless, the molecular signalling network that coordinates strategies for successful decidualization and placentation are not well understood. The discovery of the endocannabinoid system highlighted new signalling mediators in various physiological processes, including reproduction. It is known that endocannabinoids present regulatory functions during blastocyst development, oviductal transport, and implantation. In addition, all the endocannabinoid machinery was found to be expressed in decidual and placental tissues. Additionally, endocannabinoid's plasmatic levels were found to fluctuate during normal gestation and to induce decidual cell death and disturb normal placental development. Moreover, aberrant endocannabinoid signalling during the period of placental development has been associated with pregnancy disorders. It indicates the existence of a possible regulatory role for these molecules during decidualization and placentation processes, which are known to be particularly vulnerable. In this review, the influence of the endocannabinoid system in these critical processes is explored and discussed.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.