ArticleJournal of virology2014
EBP1, a novel host factor involved in primer binding site-dependent restriction of moloney murine leukemia virus in embryonic cells.
Article in Journal of virology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 25 citations in OpenAlex.
- PA2G4 in health and disease: An underestimated multifunctional regulator.Journal of advanced research · 2025Review
- KAP1 in antiviral immunity: dual roles in viral silencing and immune regulation.Frontiers in cellular and infection microbiology · 2025Review
- Article
- Trim24 and Trim33 Play a Role in Epigenetic Silencing of Retroviruses in Embryonic Stem Cells.Viruses · 2020Article
- Genome-wide CRISPR knockout screen identifies ZNF304 as a silencer of HIV transcription that promotes viral latency.PLoS pathogens · 2020Article
- Investigating the role of Ebp1 in Chandipura virus infection.Journal of biosciences · 2019Article
- A somatic role for the histone methyltransferase Setdb1 in endogenous retrovirus silencing.Nature communications · 2018Article
- Transcriptional Silencing of Moloney Murine Leukemia Virus in Human Embryonic Carcinoma Cells.Journal of virology · 2017Article
- Histones Are Rapidly Loaded onto Unintegrated Retroviral DNAs Soon after Nuclear Entry.Cell host & microbe · 2016Article
- Article
- Article
- Regulation of Yin Yang 1 by Tyrosine Phosphorylation.The Journal of biological chemistry · 2015Article
- Retrotransposons shape species-specific embryonic stem cell gene expression.Retrovirology · 2015Review
- Retroviral transcriptional regulation and embryonic stem cells: war and peace.Molecular and cellular biology · 2015Review
- Article
- Retroviral DNA Transposition: Themes and Variations.Microbiology spectrum · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
Mouse embryonic cells are unable to support the replication of Moloney murine leukemia virus (MLV). The integrated viral DNA is transcriptionally silenced, largely due to binding of host transcriptional repressors to the primer binding site (PBS) of the provirus. We have previously shown that a PBS DNA-binding repressor complex contains ZFP809 and TRIM28. Here, we identified ErbB3-binding protein 1 (EBP1) to be a novel component of the ZFP809-TRIM28 silencing complex and show that EBP1 depletion reduces PBS-mediated retroviral silencing.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.