Trial reportJournal of the National Comprehensive Cancer Network : JNCCN2013
Efficacy trial of an Internet-based intervention for cancer-related female sexual dysfunction.
Trial report in Journal of the National Comprehensive Cancer Network : JNCCN, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 56 papers, 10 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
56 citing papers in PubMed, 10 syntheses or guidelines pooled it.
- Effectiveness of Pelvic Floor Muscle and Education-based Therapies on Bladder, Bowel, Vaginal, Sexual, Psychological Function, Quality of Life, and Pelvic Floor Muscle Function in Females Treated for Breast Cancer: A Systematic Review.Current oncology reports · 2025Pooled it
- Factors Associated With Digital Intervention Engagement and Adherence in Patients With Cancer: Systematic Review.Journal of medical Internet research · 2024Pooled it
- Psychosocial interventions to improve sexual functioning in women with cancer: a systematic review of randomized controlled trials.Sexual medicine reviews · 2024Pooled it
- The effectiveness of digital psychosocial interventions on psychological distress, depression, anxiety, and health-related quality of life in patients with gynaecological cancer: a systematic review and meta-analysis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024Pooled it
- Feasibility and effectiveness of communication tools for addressing intimacy and sexuality in patients with cancer: a systematic review.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024Pooled it
- Psychosocial interventions for informal caregivers of people living with cancer.The Cochrane database of systematic reviews · 2019Pooled it
- Online-based interventions for sexual health among individuals with cancer: a systematic review.BMC health services research · 2018Pooled it
- Online support groups for women with breast cancer.The Cochrane database of systematic reviews · 2017Pooled it
- Interventions for sexual dysfunction following treatments for cancer in women.The Cochrane database of systematic reviews · 2016Pooled it
- Self-Reported Sexual Function Measures Administered to Female Cancer Patients: A Systematic Review, 2008-2014.Journal of psychosocial oncology · 2015Pooled it
- Examining recruitment differences by race, ethnicity, and age to a decentralized trial of an internet-delivered intervention for sexual health after breast cancer: the WF-2202 SHINE trial.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026Trial
- Adherence, Acceptability, and Sexual Health Outcomes of the Odeya App-Based Intervention for Sexual Distress in Women With Endometriosis: Randomized Controlled Mixed Methods Trial.Journal of medical Internet research · 2026Trial
- The web-based Pleasure&Pregnancy programme in the treatment of unexplained infertility: a randomized controlled trial.Human reproduction (Oxford, England) · 2024Trial
- An online randomized controlled trial, with or without problem-solving treatment, for long-term cancer survivors after hematopoietic cell transplantation.Journal of cancer survivorship : research and practice · 2018Trial
- A pilot randomized trial to prevent sexual dysfunction in postmenopausal breast cancer survivors starting adjuvant aromatase inhibitor therapy.Journal of cancer survivorship : research and practice · 2017Trial
- The sexual health of female rectal and anal cancer survivors: results of a pilot randomized psycho-educational intervention trial.Journal of cancer survivorship : research and practice · 2016Trial
- Trial
- A randomized pilot trial of a couple-based intervention addressing sexual concerns for breast cancer survivors.Journal of psychosocial oncologyTrial
- Clinical practice guidelines: sexual dysfunction in gynecological cancer patients.Sexual medicine · 2025Review
- Enhancing nurses' communication about psychosocial needs and changes in intimacy and sexuality in patients with advanced cancer: a mixed-method study.International journal of nursing studies advances · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
The recent NCCN Guidelines for Survivorship recommend systematic evaluation and multidisciplinary treatment of cancer-related sexual dysfunctions. However, most oncology professionals fail to routinely assess sexual problems and lack expertise to treat them. An Internet-based intervention was designed to educate female patients and their partners about cancer-related sexual problems, describe medical treatment options and how to find expert care, and provide self-help strategies. A randomized trial assessed efficacy of the intervention when used as self-help versus the same Web access and 3 supplemental counseling sessions. Survivors of localized breast or gynecologic cancers completed online questionnaires at baseline, posttreatment, and 3- and 6-month follow-up, including the Female Sexual Function Index (FSFI), the Menopausal Sexual Interest Questionnaire (MSIQ), the Brief Symptom Inventory-18 (BSI-18) to assess emotional distress, and the Quality of Life in Adult Cancer Survivors (QLACS) scale. Program evaluation ratings were completed posttreatment. Fifty-eight women completed baseline questionnaires (mean age, 53 ± 9 years). Drop-out rates were 22% during treatment and 34% at 6-month follow-up. Linear mixed models for each outcome across time showed improvement in total scores on the FSFI, MSIQ, and QLACS (P<.001) and BSI-18 (P=.001). The counseled group improved significantly more on sexuality measures, but changes in emotional distress and quality of life did not differ between groups. Program content and ease of use were rated positively. Research is needed on how best to integrate this intervention into routine clinical practice, and particularly how to improve uptake and adherence.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.