Evidence map›Paper›PMID 24225723›Full record

ArticleEnvironmental health perspectives2014

Air pollution exposures during adulthood and risk of endometriosis in the Nurses' Health Study II.

Shruthi Mahalingaiah, Jaime E Hart, Francine Laden, Ann Aschengrau, Stacey A Missmer

Open access · diamondAbstract read
In one paragraph

Article in Environmental health perspectives, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 2 pooled it
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 2 syntheses or guidelines pooled it, 22 citations in OpenAlex.

  1. Pooled it
  2. Characteristics of cohort studies of long-term exposure to PMEnvironmental science and pollution research international · 2019
    Pooled it
  3. Article
  4. Article
  5. Endometriosis and cardiovascular disease.European heart journal open · 2022
    Article
  6. Article
  7. Article
  8. Perimenarchal air pollution exposure and menstrual disorders.Human reproduction (Oxford, England) · 2018
    Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Shruthi MahalingaiahDepartment of Obstetrics and Gynecology, Boston University School of Medicine, Boston, Massachusetts, USA.
Jaime E Hart
Francine Laden
Ann Aschengrau
Stacey A Missmer
Brigham and Women's Hospital · USBoston University · US

Funding

Training CoreP42ES007381 · NIEHS · BOSTON UNIVERSITY MEDICAL CAMPUS · PI SCHLEZINGER, JENNIFER J · 1995 to 2019
$46.1M
REPRODUCTIVE SCIENTIST TRAINING PROGRAMK12HD000849 · NICHD · WASHINGTON UNIVERSITY · PI Danny J Schust · 1988 to 2026
$33.2M
Risk Factors for Breast Cancer in Younger NursesR01CA050385 · NCI · HARVARD UNIVERSITY (SCH OF PUBLIC HLTH) · PI ELIASSEN, A. HEATHER, WILLETT, WALTER C. · 1989 to 2019
$32.3M
Life Course Cancer Epidemiology Cohort in WomenUM1CA176726 · NCI · HARVARD SCHOOL OF PUBLIC HEALTH · PI WILLETT, WALTER C. · 2013 to 2017
$15.7M
Interdisciplinary Research Careers in Women's HealthK12HD043444 · NICHD · BOSTON UNIVERSITY MEDICAL CAMPUS · PI SILLIMAN, REBECCA A · 2002 to 2011
$5.0M
DIET, PHYSICAL ACTIVITY, AND THE RELATIONSHIP BETWEEN AIR POLLUTION AND CVDR01ES017017 · NIEHS · BRIGHAM AND WOMEN'S HOSPITAL · PI LADEN, FRANCINE · 2009 to 2012
$1.7M
Immunology, Inflammation, and EndometriosisR01HD057210 · NICHD · BRIGHAM AND WOMEN'S HOSPITAL · PI MISSMER, STACEY ANN · 2009 to 2012
$1.4M
NCI NIH HHS R01 CA050385NCI NIH HHS R01CA50385NCI NIH HHS UM1 CA176726NICHD NIH HHS 5K12HD043444-10NICHD NIH HHS K12 HD000849NICHD NIH HHS K12 HD043444NICHD NIH HHS R01 HD057210NICHD NIH HHS R01HD57210NIEHS NIH HHS 5R01ES017017NIEHS NIH HHS L30 ES023231NIEHS NIH HHS P42 ES007381NIEHS NIH HHS R01 ES017017
6 · The paper itself

Abstract

backgroundParticulate matter and proximity to large roadways may promote disease mechanisms, including systemic inflammation, hormonal alteration, and vascular proliferation, that may contribute to the development and severity of endometriosis.

objectiveOur goal was to determine the association of air pollution exposures during adulthood, including distance to road, particulate matter<2.5 μm, between 2.5 and 10 μm, and <10 μm, (PM2.5, PM10-2.5, PM10), and timing of exposure with risk of endometriosis in the Nurses' Health Study II.

methodsProximity to major roadways and outdoor levels of PM2.5, PM10-2.5, and PM10 were determined for all residential addresses from 1993 to 2007. Multivariable-adjusted time-varying Cox proportional hazard models were used to estimate the relation between these air pollution exposures and endometriosis risk.

resultsAmong 84,060 women, 2,486 incident cases of surgically confirmed endometriosis were identified over 710,230 person-years of follow-up. There was no evidence of an association between endometriosis risk and distance to road or exposure to PM2.5, PM10-2.5, or PM10 averaged over follow-up or during the previous 2- or 4-year period.

conclusionsTraffic and air pollution exposures during adulthood were not associated with incident endometriosis in this cohort of women.

Indexed as

AdultAir PollutantsAir PollutionEndometriosisEnvironmental ExposureFemaleHumansParticulate MatterProportional Hazards ModelsAir PollutantsParticulate Matter

Identifiers

PMID24225723
PMCPMC3888567
OpenAlexW2149418475

What OpenQuestion holds

Textmetadata
LicenceCC0
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.