Trial reportArchives of suicide research : official journal of the International Academy for Suicide Research2013
Regional brain glucose uptake distinguishes suicide attempters from non-attempters in major depression.
Trial report in Archives of suicide research : official journal of the International Academy for Suicide Research, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
35 citing papers in PubMed.
- The effect of once-daily vs. twice-daily intermittent theta burst stimulation on suicidal ideation in treatment-resistant depression.European archives of psychiatry and clinical neuroscience · 2025Trial
- Placebo aiTBS attenuates suicidal ideation and frontopolar cortical perfusion in major depression.Translational psychiatry · 2019Trial
- Uncovering oscillatory dysregulation associated with suicide risk in major depressive disorder: a narrative review.Translational psychiatry · 2026Review
- Negative family and interpersonal relationship are associated with centromedial amygdala functional connectivity alterations in adolescent depression.European child & adolescent psychiatry · 2024Article
- U-shaped association between fasting blood glucose and suicide attempts in Chinese patients with first-episode drug-naïve major depressive disorder.BMC psychiatry · 2024Article
- Prevalence, risk factors and clinical correlates of glucose disturbances in a large sample of Han Chinese patients with first-episode drug-naïve major depressive disorder.European archives of psychiatry and clinical neuroscience · 2024Article
- Distinct correlation network of clinical characteristics in suicide attempters having adolescent major depressive disorder with non-suicidal self-injury.Translational psychiatry · 2024Article
- The left-lateralisation of citrate synthase activity in the anterior cingulate cortex of male violent suicide victims.European archives of psychiatry and clinical neuroscience · 2023Article
- Examining differences in brain metabolism associated with childhood maltreatment and suicidal attempt in euthymic patients with bipolar disorder: A PET and Machine Learning Study.Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999) · 2023Article
- Metabolic parameters and thyroid hormones in relation to suicide attempts in patients with first-episode and drug-naive major depressive disorder with comorbid glucose disturbances: a large cross-sectional study.European archives of psychiatry and clinical neuroscience · 2023Article
- Prevalence and influencing factors of suicide in first-episode and drug-naive young major depressive disorder patients with impaired fasting glucose: a cross-sectional study.Frontiers in psychiatry · 2023Article
- Altered resting-state cerebral blood flow and functional connectivity mediate suicidal ideation in major depressive disorder.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2022Article
- Aberrant resting-state functional connectivity of major depressive disorder with higher risk of suicide.PCN reports : psychiatry and clinical neurosciences · 2022Article
- Altered functional connectivity density and couplings in postpartum depression with and without anxiety.Social cognitive and affective neuroscience · 2022Article
- The Role of the Anterior Cingulate Cortex and Insular Cortex in Suicidal Memory and Intent.Cureus · 2021Article
- Suicide Risk and Addiction: The Impact of Alcohol and Opioid Use Disorders.Current addiction reports · 2021Review
- Article
- Atrophy of right inferior frontal orbital gyrus and frontoparietal functional connectivity abnormality in depressed suicide attempters.Brain imaging and behavior · 2020Article
- Caudothalamic dysfunction in drug-free suicidally depressed patients: an MEG study.European archives of psychiatry and clinical neuroscience · 2020Article
- Frontal Alpha Asymmetry Moderated by Suicidal Ideation in Patients with Major Depressive Disorder: A Comparison with Healthy Individuals.Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology · 2020Article
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
This study compared regional cerebral metabolic rates of glucose (rCMRglu) determined by [(18)F]-fluoro-2-deoxyglucose positron emission tomography (FDG-PET) in suicide attempters and non-attempters. Medication-free patients with major depression (n = 29) had FDG-PET after single-blind administration of placebo (day 1) and fenfluramine (day 2). Suicide attempt history was obtained before scanning and at assessments over 2 subsequent years. Statistical parametric mapping evaluated associations between attempt status and rCMRglu, controlling for age. The study included 13 patients with and 16 without a history of suicide attempt within 2 years before or after scanning. After placebo, rCMRglu in attempters was lower in right dorsolateral prefrontal regions and higher in ventromedial regions than in non-attempters. After fenfluramine, relatively hypometabolic areas enlarged, and no hypermetabolic areas were detected. Distinct rCMRglu patterns may be serotonin-sensitive biomarkers of suicide risk.
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