Evidence map›Paper›PMID 24224118›Full record

ArticleJournal of AIDS & clinical research2013

Meta-Analysis of Interventions for Reducing Number of Sexual Partners and Drug and Alcohol Abuse among People Living with HIV/AIDS.

Na Wang, Xiaoyun Sun, Lu Yin, Hongjie Liu, Yuhua Ruan, Yiming Shao, Han-Zhu Qian, Sten H Vermund

Abstract read
In one paragraph

Article in Journal of AIDS & clinical research, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 2 pooled it
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 2 syntheses or guidelines pooled it, 10 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Trial
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Na WangNational Center for AIDS/STD Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China.
Xiaoyun Sun
Lu Yin
Hongjie Liu
Yuhua Ruan
Yiming Shao
Han-Zhu Qian
Sten H Vermund

Funding

Structural insight into novel mechanisms of type III secretionR01AI094623 · NIAID · UNIVERSITY OF MINNESOTA · PI KALODIMOS, CHARALAMPOS · 2012 to 2023
$4.0M
SIV Transmission in Male NHPR01AI094620 · NIAID · UNIVERSITY OF CALIFORNIA AT DAVIS · PI MILLER, CHRISTOPHER JAMES · 2011 to 2015
$3.5M
Multi-component HIV Intervention Packages for Chinese MSMR01AI094562 · NIAID · VANDERBILT UNIVERSITY MEDICAL CENTER · PI QIAN, HAN-ZHU, VERMUND, STEN H. · 2011 to 2014
$2.5M
Expanded Testing, Linkage, and Treatment for HIV Prevention Among MSM in ChinaR34AI091446 · NIAID · VANDERBILT UNIVERSITY · PI VERMUND, STEN H. · 2011 to 2011
$226k
FUNCTION OF AND SIGNALING BY THE B CELL PROTEINF32AI009462 · NIAID · STANFORD UNIVERSITY · PI PAN, CHIN · 1996 to 1996
–
NIAID NIH HHS F32 AI009462NIAID NIH HHS R01 AI094562NIAID NIH HHS R01 AI094620NIAID NIH HHS R01 AI094623NIAID NIH HHS R34 AI091446
6 · The paper itself

Abstract

objectiveTo perform a systematic review and meta-analysis of the efficacy of risk reduction interventions on HIV-related risk behaviors among people living with HIV/AIDS (PLWHA).

methodsStudies included in the meta-analysis were randomized clinical trials (RCTs) of risk reduction interventions, which targeted PLWHA aged 18 year or older and assessed the changes of number of sexual partners, drug use, needle sharing, and/or alcohol abuse between pre- and post-intervention. The standardized mean differences (SMD) between study arms as well as between baseline and post-intervention, defined as the effect sizes (ES), were calculated in random effects models. Heterogeneity of studies was estimated by the

resultsTwelve RCTs involving 3993 PLWHA were included in our analysis: seven reported impacts on the number of sexual partners, and three reported impacts on drug use, needle sharing, and alcohol abuse, respectively. There were no statistically significant impacts of risk reduction interventions on the number of total sexual partners (mean ES, -0.10; 95% confidence interval [CI], -0.26, 0.06;

conclusionsOur meta-analysis did not find a positive impacts of risk reduction interventions on number of sexual partners, drug use, needle sharing, or alcohol abuse among PLWHA, but the small number of studies meeting our review criteria limits these findings.

Indexed as

Alcohol abuseDrug useMeta-analysisPeople living with HIV/AIDS (PLWHA)Positive preventionRandomized clinical trial (RCT)Sexual partners

Identifiers

PMID24224118
PMCPMC3819193
OpenAlexW2048710267

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.