Evidence map›Paper›PMID 24224084›Full record

ArticlePhysiological reports2013

Angiotensin II Stimulates Sympathetic Neurotransmission to Adipose Tissue.

Victoria L King, Victoria L English, Kalyani Bharadwaj, Lisa A Cassis

Open access · goldAbstract read
In one paragraph

Article in Physiological reports, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
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  4. Validity of mental and physical stress models.Neuroscience and biobehavioral reviews · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Victoria L KingDivision of Cardiology, University of Kentucky, Lexington, KY 40536.
Victoria L English
Kalyani Bharadwaj
Lisa A Cassis
University of Kentucky · USPiramal (India) · IN

Funding

Angiotensin: A Link Between Obesity and HypertensionR01HL073085 · NHLBI · UNIVERSITY OF KENTUCKY · PI CASSIS, LISA A · 2003 to 2017
$5.0M
Angiotensin/Sympathetic Interactions and Blood PressureR01HL064121 · NHLBI · UNIVERSITY OF KENTUCKY · PI CASSIS, LISA A · 2001 to 2004
$1.2M
NHLBI NIH HHS R01 HL064121NHLBI NIH HHS R01 HL073085
6 · The paper itself

Abstract

Angiotensin II (AngII) facilitates sympathetic neurotransmission by regulating norepinephrine (NE) synthesis, release and uptake. These effects of AngII contribute to cardiovascular control. Previous studies in our laboratory demonstrated that chronic AngII infusion decreased body weight of rats. We hypothesized that AngII facilitates sympathetic neurotransmission to adipose tissue and may thereby decrease body weight. The effect of chronic AngII infusion on the NE uptake transporter and NE turnover was examined in metabolic (interscapular brown adipose tissue, ISBAT; epididymal fat, EF) and cardiovascular tissues (left ventricle, LV; kidney) of rats. To examine the uptake transporter saturation isotherms were performed using [

Indexed as

body weightcatecholamine turnovernorepinephrine

Identifiers

PMID24224084
PMCPMC3818081
OpenAlexW2121621776

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.