ArticlePloS one2013
A prospective cohort study examining the associations of dietary calcium intake with all-cause and cardiovascular mortality in older Chinese community-dwelling people.
Article in PloS one, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 2 of them syntheses that pooled it.
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Who cites it
16 citing papers in PubMed, 2 syntheses or guidelines pooled it, 34 citations in OpenAlex.
- Calcium intake, calcium supplementation and cardiovascular disease and mortality in the British population: EPIC-norfolk prospective cohort study and meta-analysis.European journal of epidemiology · 2021Pooled it
- Dietary calcium intake and mortality risk from cardiovascular disease and all causes: a meta-analysis of prospective cohort studies.BMC medicine · 2014Pooled it
- Dietary Calcium to Magnesium Ratio and Risk of Cardiovascular Diseases.Biological trace element research · 2025Article
- Association between dietary quality index-international (DQI-I) and cardiovascular diseases: insights from RaNCD cohort study.BMC nutrition · 2025Article
- Mineral Intake and Cardiovascular Disease, Cancer, and All-Cause Mortality: Findings from the Golestan Cohort Study.Nutrients · 2024Article
- Association of dietary calcium with mortality from all causes, cardiovascular disease and cancer in people with hypertension.Journal of clinical hypertension (Greenwich, Conn.) · 2023Article
- Higher Lead and Lower Calcium Levels Are Associated with Increased Risk of Mortality in Malaysian Older Population: Findings from the LRGS-TUA Longitudinal Study.International journal of environmental research and public health · 2022Article
- Dietary patterns generated by the Treelet Transform and risk of stroke: a Danish cohort study.Public health nutrition · 2021Article
- The good, the bad, and the ugly of calcium supplementation: a review of calcium intake on human health.Clinical interventions in aging · 2018Review
- Dietary Calcium Intake May Contribute to the HOMA-IR Score in Korean Females with Vitamin D Deficiency (2008-2012 Korea National Health and Nutrition Examination Survey).Journal of obesity & metabolic syndrome · 2017Article
- Calcium supplementation and cardiovascular risk: A rising concern.Journal of clinical hypertension (Greenwich, Conn.) · 2017Review
- Prevalence of stroke and associated risk factors among middle-aged and older farmers in western China.Environmental health and preventive medicine · 2017Article
- Racial Differences in Association of Serum Calcium with Mortality and Incident Cardio- and Cerebrovascular Events.The Journal of clinical endocrinology and metabolism · 2016Article
- Lack of association of oral calcium supplementation with coronary artery calcification in rheumatoid arthritis.Arthritis & rheumatology (Hoboken, N.J.) · 2015Article
- Osteoporosis knowledge, self-efficacy, and health beliefs among Chinese individuals with HIV.Archives of osteoporosis · 2014Article
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundMost epidemiological studies of calcium intake and mortality risk have been conducted in populations with moderate to high calcium intake, and limited studies have focused on populations with low habitual calcium intake (i.e., mean dietary calcium intake <700 mg/d).
objectiveThis study investigated the association between dietary calcium intake and death from all causes and cardiovascular disease in Chinese population with low habitual calcium intake.
designData from 3,139 Chinese men and women in a population-based prospective cohort study, aged >=65 years and free of heart diseases or stroke at baseline, were analyzed. Primary outcome measures, identified from the death registry, were death from all causes and cardiovascular disease. Dietary calcium intake assessed using a validated food frequency questionnaire was categorized into sex-specific quartiles. Data on use of supplemental calcium (yes or no) including individual calcium supplements and other calcium containing supplement were collected. Cox regression models adjusted for demographic and lifestyle variables were used to estimate hazard ratios (HRs) and 95% confidence intervals (CI).
resultsDuring a median of 9.1 years of follow-up, 529 all-cause deaths (344 men, 185 women) and 114 (74 men, 40 women) deaths from cardiovascular disease were identified. An inverse trend between dietary calcium intake and mortality was observed. Compared with the lowest quartile (<458 mg/d for men, <417 mg/d for women), the highest quartile of dietary calcium intake (>762 mg/d for men, >688 mg/d for women) had a significantly reduced risk of all-cause mortality (multivariate HR=0.63, 95% CI=0.49-0.81, P(trend)<0.001) but an insignificant decreased risk of cardiovascular mortality (multivariate HR=0.70, 95% CI=0.41-1.21, P(trend)=0.228). Similar inverse association was observed when the analyses were stratified on calcium supplemental use.
conclusionsHigher intake of dietary calcium was associated with reduced risk of all-cause mortality and possibly cardiovascular mortality in Chinese older people with low habitual calcium intake.
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