ArticlePloS one2013
Novel B19-like parvovirus in the brain of a harbor seal.
Article in PloS one, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 30 citations in OpenAlex.
- Discovery of a human parvovirus B19 analog (Erythroparvovirus) in cats.Scientific reports · 2025Article
- Hepatovirus infections in juvenile seals from the North Sea.Npj viruses · 2025Article
- Neurological examination of Pacific harbor seal (Frontiers in veterinary science · 2025Article
- Exploring viral diversity in diarrheic porcine feces: a metagenomic analysis from an Indian swine farm.Frontiers in cellular and infection microbiology · 2025Article
- A systematic review on global zoonotic virus-associated mortality events in marine mammals.One health (Amsterdam, Netherlands) · 2024Review
- Highly pathogenic avian influenza A virus (HPAIV) H5N1 infection in two European grey seals (Emerging microbes & infections · 2023Article
- Small but mighty: old and new parvoviruses of veterinary significance.Virology journal · 2021Review
- Taxonomic update for mammalian anelloviruses (family Anelloviridae).Archives of virology · 2021Article
- Novel anelloviruses identified in buccal swabs of Antarctic fur seals.Virus genes · 2018Article
- Viruses associated with Antarctic wildlife: From serology based detection to identification of genomes using high throughput sequencing.Virus research · 2018Review
- Norovirus Infection in Harbor Porpoises.Emerging infectious diseases · 2017Article
- Diverse and highly recombinant anelloviruses associated with Weddell seals in Antarctica.Virus evolution · 2017Article
- Current Advances on Virus Discovery and Diagnostic Role of Viral Metagenomics in Aquatic Organisms.Frontiers in microbiology · 2017Review
- Central nervous system disease and genital disease in harbor porpoises (Phocoena phocoena) are associated with different herpesviruses.Veterinary research · 2016Article
- Article
- Metagenomic Survey of Viral Diversity Obtained from Feces of Subantarctic and South American Fur Seals.PloS one · 2016Article
- Molecular epidemiology of seal parvovirus, 1988-2014.PloS one · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
14 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Using random PCR in combination with next-generation sequencing, a novel parvovirus was detected in the brain of a young harbor seal (Phoca vitulina) with chronic non-suppurative meningo-encephalitis that was rehabilitated at the Seal Rehabilitation and Research Centre (SRRC) in the Netherlands. In addition, two novel viruses belonging to the family Anelloviridae were detected in the lungs of this animal. Phylogenetic analysis of the coding sequence of the novel parvovirus, tentatively called Seal parvovirus, indicated that this virus belonged to the genus Erythrovirus, to which human parvovirus B19 also belongs. Although no other seals with similar signs were rehabilitated in SRRC in recent years, a prevalence study of tissues of seals from the same area collected in the period 2008-2012 indicated that the Seal parvovirus has circulated in the harbor seal population at least since 2008. The presence of the Seal parvovirus in the brain was confirmed by real-time PCR and in vitro replication. Using in situ hybridization, we showed for the first time that a parvovirus of the genus Erythrovirus was present in the Virchow-Robin space and in cerebral parenchyma adjacent to the meninges. These findings showed that a parvovirus of the genus Erythrovirus can be involved in central nervous system infection and inflammation, as has also been suspected but not proven for human parvovirus B19 infection.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.