ArticlePloS one2013
Recurrence of preeclampsia in northern Tanzania: a registry-based cohort study.
Article in PloS one, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 3 of them syntheses that pooled it.
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Who cites it
10 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Epidemiology of preterm birth in Ethiopia: systematic review and meta-analysis.BMC pregnancy and childbirth · 2020Pooled it
- Clinical risk factors for pre-eclampsia determined in early pregnancy: systematic review and meta-analysis of large cohort studies.BMJ (Clinical research ed.) · 2016Pooled it
- Prevalence of hypertensive disorders of pregnancy and pregnancy outcomes in Sub-Saharan Africa: A systematic review and meta-analysis.Women's health (London, England)Pooled it
- Predictors of maternal and perinatal mortality among pregnant women with preeclampsia and eclampsia at Garissa County Referral Hospital: a retrospective cohort study.BMC pregnancy and childbirth · 2026Article
- Are Overweight and Obesity Risk Factors for Developing Metabolic Syndrome or Hypertension after a Preeclamptic Event?Healthcare (Basel, Switzerland) · 2023Article
- Risk of Subsequent Preeclampsia by Maternal Country of Birth: A Norwegian Population-Based Study.International journal of environmental research and public health · 2023Article
- Comparative risks and predictors of preeclamptic pregnancy in the Eastern, Western and developing world.Biochemical pharmacology · 2020Review
- Maternal obesity and intrapartum obstetric complications among pregnant women: Retrospective cohort analysis from medical birth registry in Northern Tanzania.Obesity science & practice · 2020Article
- Incidence and recurrence risk of low birth weight in Northern Tanzania: A registry based study.PloS one · 2019Article
- A KIR B centromeric region present in Africans but not Europeans protects pregnant women from pre-eclampsia.Proceedings of the National Academy of Sciences of the United States of America · 2015Article
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivePreeclampsia occurs in about 4 per cent of pregnancies worldwide, and may have particularly serious consequences for women in Africa. Studies in western countries have shown that women with preeclampsia in one pregnancy have a substantially increased risk of preeclampsia in subsequent pregnancies. We estimate the recurrence risks of preeclampsia in data from Northern Tanzania.
methodsA prospective cohort study was designed using 19,811 women who delivered singleton infants at a hospital in Northern Tanzania between 2000 and 2008. A total of 3,909 women were recorded with subsequent deliveries in the hospital with follow up through 2010. Adjusted recurrence risks of preeclampsia were computed using regression models.
resultsThe absolute recurrence risk of preeclampsia was 25%, which was 9.2-fold (95% CI: 6.4 - 13.2) compared with the risk for women without prior preeclampsia. When there were signs that the preeclampsia in a previous pregnancy had been serious either because the baby was delivered preterm or had died in the perinatal period, the recurrence risk of preeclampsia was even higher. Women who had preeclampsia had increased risk of a series of adverse pregnancy outcomes in future pregnancies. These include perinatal death (RR= 4.3), a baby with low birth weight (RR= 3.5), or a preterm birth (RR= 2.5). These risks were only partly explained by recurrence of preeclampsia.
conclusionsPreeclampsia in one pregnancy is a strong predictor for preeclampsia and other adverse pregnancy outcomes in subsequent pregnancies in Tanzania. Women with previous preeclampsia may benefit from close follow-up during their pregnancies.
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