ArticleFrontiers in neurology2013
FMRI of working memory impairment after recovery from subarachnoid hemorrhage.
Article in Frontiers in neurology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
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Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Magnetic Resonance Imaging in Aneurysmal Subarachnoid Hemorrhage: Current Evidence and Future Directions.Neurocritical care · 2018Pooled it
- Telomere length as a predictive marker for long-term cognitive function in a mouse model of subarachnoid hemorrhage.Neural regeneration research · 2026Article
- Article
- Brain activation patterns in patients with post-stroke cognitive impairment during working memory task: a functional near-infrared spectroscopy study.Frontiers in neurology · 2024Article
- SIRT1 mediates hypoxic postconditioning- and resveratrol-induced protection against functional connectivity deficits after subarachnoid hemorrhage.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2022Article
- Subarachnoid hemorrhage leads to early and persistent functional connectivity and behavioral changes in mice.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2021Article
- A functional MRI study of presurgical cognitive deficits in glioma patients.Neuro-oncology practice · 2021Article
- Topological Alterations of Working Memory Impairment in Aged Patients With Vascular Dementia.Frontiers in aging neuroscience · 2021Article
- Article
- Neurobehavioral testing in subarachnoid hemorrhage: A review of methods and current findings in rodents.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2017Review
- Altered Resting-State Connectivity within Executive Networks after Aneurysmal Subarachnoid Hemorrhage.PloS one · 2015Article
- Aneurysmal subarachnoid haemorrhage from a neuroimaging perspective.Critical care (London, England) · 2014Review
- The role of microclot formation in an acute subarachnoid hemorrhage model in the rabbit.BioMed research international · 2014Article
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Authors and funding
3 authors.
Funding
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Abstract
Recovery from aneurysmal subarachnoid hemorrhage (SAH) is often incomplete and accompanied by subtle but persistent cognitive deficits. Previous neuropsychological reports indicate these deficits include most prominently memory impairment, with working memory particularly affected. The neural basis of these memory deficits remains unknown and unexplored by functional magnetic resonance imaging (fMRI). In the present study, patients who experienced (SAH) underwent fMRI during the performance of a verbal working memory paradigm. Behavioral results indicated a subtle but statistically significant impairment relative to healthy subjects in working memory performance accuracy, which was accompanied by relatively increased blood-oxygen level dependent signal in widespread left and right hemisphere cortical areas during periods of encoding, maintenance, and retrieval. Activity increases remained after factoring out inter-individual differences in age and task performance, and included most notably left hemisphere regions associated with phonological loop processing, bilateral sensorimotor regions, and right hemisphere dorsolateral prefrontal cortex. We conclude that deficits in verbal working memory following recovery from (SAH) are accompanied by widespread differences in hemodynamic correlates of neural activity. These differences are discussed with respect to the immediate and delayed focal and global brain damage that can occur following (SAH), and the possibility that this damage induces subcortical disconnection and subsequent decreased efficiency in neural processing.
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