ReviewFrontiers in cellular neuroscience2013
Novel ncRNAs transcribed by Pol III and elucidation of their functional relevance by biophysical approaches.
Review in Frontiers in cellular neuroscience, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 22 citations in OpenAlex.
- Untangling the Genetic Threads of Alzheimer's: Insights into Risk Factors and Biomarkers.Current gene therapy · 2025Review
- Insights into the mechanisms of non-coding RNAs' implication in the pathogenesis of Alzheimer's disease.EXCLI journal · 2022Review
- RNA Dynamics in Alzheimer's Disease.Molecules (Basel, Switzerland) · 2021Review
- Long Non-Coding RNA (lncRNA) Roles in Cell Biology, Neurodevelopment and Neurological Disorders.Non-coding RNA · 2021Review
- Meet the editor series-Massimo Vassalli.Biophysical reviews · 2021Article
- Molecular mechanisms underlying actions of certain long noncoding RNAs in Alzheimer's disease.Metabolic brain disease · 2020Review
- Integrated identification of key genes and pathways in Alzheimer's disease via comprehensive bioinformatical analyses.Hereditas · 2019Article
- The Role of Long Noncoding RNAs in Diabetic Alzheimer's Disease.Journal of clinical medicine · 2018Article
- Plasma long non-coding RNA BACE1 as a novel biomarker for diagnosis of Alzheimer disease.BMC neurology · 2018Article
- Generation of a Functional Human Neural Network by NDM29 Overexpression in Neuroblastoma Cancer Cells.Molecular neurobiology · 2017Article
- Long noncoding RNAs and Alzheimer's disease.Clinical interventions in aging · 2016Review
- Perhexiline maleate enhances antitumor efficacy of cisplatin in neuroblastoma by inducing over-expression of NDM29 ncRNA.Scientific reports · 2015Article
- Editorial for "Regulatory RNAs in the nervous system".Frontiers in cellular neuroscience · 2015Article
- Atomic force microscopy as an advanced tool in neuroscience.Translational neuroscience · 2015Review
- The new world of RNAs.Genetics and molecular biology · 2014Review
- Metformin inhibition of neuroblastoma cell proliferation is differently modulated by cell differentiation induced by retinoic acid or overexpression of NDM29 non-coding RNA.Cancer cell international · 2014Article
Corrections and comments
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Authors and funding
4 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In the last decade the role of non coding (nc) RNAs in neurogenesis and in the onset of neurological diseases has been assessed by a multitude of studies. In this scenario, approximately 30 small RNA polymerase (pol) III-dependent ncRNAs were recently identified by computational tools and proposed as regulatory elements. The function of several of these transcripts was elucidated in vitro and in vivo confirming their involvement in cancer and in metabolic and neurodegenerative disorders. Emerging biophysical technologies together with the introduction of a physical perspective have been advantageous in regulatory RNA investigation providing original results on: (a) the differentiation of neuroblastoma (NB) cells towards a neuron-like phenotype triggered by Neuroblastoma Differentiation Marker 29 (NDM29) ncRNA; (b) the modulation of A-type K(+) current in neurons induced by the small ncRNA 38A and (c) the synthesis driven by 17A ncRNA of a GABAB2 receptor isoform unable to trigger intracellular signaling. Moreover, the application of Single Cell Force Spectroscopy (SCFS) to these studies suggests a correlation between the malignancy stage of NB and the micro-adhesive properties of the cells, allowing to investigate the molecular basis of such a correlation.
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