ArticleAnesthesiology and pain medicine2013
Intravenous paracetamol for postoperative analgesia in laparoscopic cholecystectomy.
Article in Anesthesiology and pain medicine, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.
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Who cites it
17 citing papers in PubMed, 2 syntheses or guidelines pooled it, 65 citations in OpenAlex.
- Single dose intravenous paracetamol or intravenous propacetamol for postoperative pain.The Cochrane database of systematic reviews · 2016Pooled it
- Transversus abdominis-plane block versus local anesthetic wound infiltration in lower abdominal surgery: a systematic review and meta-analysis of randomized controlled trials.BMC anesthesiology · 2014Pooled it
- Article
- Evaluation of the Efficacy of Intravenous Infusion of 1000 mg Paracetamol as Intrapartum Labor Analgesia.Journal of pharmacy & bioallied sciences · 2025Article
- Evaluation of the Effect of New Multimodal Analgesia Regimen for Cardiac Surgery: A Prospective, Randomized Controlled, Single-Center Clinical Study [Response to Letter].Drug design, development and therapy · 2023Article
- Analgesic effect of ketorolac added to lidocaine in surgery of traumatic arm injuries: A double-blind, randomized clinical trial.European journal of translational myology · 2022Article
- Enhanced Recovery After Surgery: Opioid Sparing Strategies After Discharge: A Review.Current pain and headache reports · 2022Review
- Perianesthetic Management of Laparoscopic Kidney Surgery.Current urology reports · 2018Review
- Comparison of intraperitoneal bupivacaine, acetazolamide, and placebo on pain relief after laparoscopic cholecystectomy surgery: A clinical trial.Medical journal of the Islamic Republic of Iran · 2018Article
- Post-Operative Pain Management in Patients Undergoing Robotic Urological Surgery.Current urology · 2016Review
- Intraperitoneal Bupivacaine-Meperidine Infiltration Versus Intravenous Paracetamol: A Comparison of Analgesic Efficacy in Post-Gynecologic Diagnostic Laparoscopic Pain.Anesthesiology and pain medicine · 2015Article
- Comparison of the analgesic effect of intravenous paracetamol/midazolam and fentanyl in preparation of patients for colonoscopy: A double blind randomized clinical trial.Caspian journal of internal medicine · 2015Article
- Comparing the effects of morphine sulfate and diclofenac suppositories on postoperative pain in coronary artery bypass graft patients.Anesthesiology and pain medicine · 2014Article
- The effect of single-dose administration of dexamethasone on postoperative pain in patients undergoing laparoscopic cholecystectomy.Anesthesiology and pain medicine · 2014Article
- Analgesic effects of paracetamol and morphine after elective laparotomy surgeries.Anesthesiology and pain medicine · 2014Article
- Transversus abdominis plane block for postoperative analgesia after laparoscopic surgery: a systematic review and meta-analysis.International journal of clinical and experimental medicine · 2014Article
- Intermittent Transcutaneous Electrical Nerve Stimulation versus Transversus Abdominis Plane Block for Postoperative Analgesia after Infraumbilical Surgeries.Anesthesia, essays and researchesArticle
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAlthough opioids are the main choice for acute postoperative pain control, many side effects have been reported for them. NSAIDs and paracetamol have been used extensively as alternatives, and it seems that they are more effective for minor to moderate pain control postoperatively when have been used alone or in combination with opioids. As laparoscopic cholecystectomy poses moderate pain postoperatively, this study was planned to assess whether paracetamol is able to provide effective analgesia as a sole analgesic at least in the first few hours post operatively.
objectivesWe evaluated the effect of intravenous Paracetamol on postoperative pain in patients undergoing laparoscopic cholecystectomy. PATIENTS AND
methodsThis is a randomized double- blind clinical trial study. 30 patients ASA class I, aged 18 to 50 years, candidate for laparoscopic cholecystectomy were recruited, and randomly divided into two equal groups. Group A (paracetamol group) received 1 gr paracetamol and group B received placebo ten minutes after the induction of anesthesia. 0.1 mg/Kg Morphine was administered intravenously based on patients compliant and pain score >3. Pain score and the opioids consumption were recorded in the first six hours postoperative. Patient's pain was measured by the VAS (Visual Analog Scale).
resultsThe pain score was lower in group A (P= 0.01), but the morphine consumption showed no significant difference between the groups (P= 0.24) during the first 6 hours postoperatively.
conclusionsAlthough paracetamol (1gr) has caused a better pain relief quality but it is not a suitable analgesic for moderate pain control in acute phase after surgery alone.
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