ArticleAnesthesiology and pain medicine2012
Does analgesic effect of opium hamper the adverse effects of severe coronary artery disease on quality of life in addicted patients?
Article in Anesthesiology and pain medicine, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
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Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The effects of opium on the cardiovascular system: a review of side effects, uses, and potential mechanisms.Substance abuse treatment, prevention, and policy · 2020Pooled it
- Metabolic profiles associated with opioid use and opioid use disorder: a narrative review of the literature.Current addiction reports · 2023Article
- Cardiovascular Complications of Chronic Opium Consumption: A Narrative Review Article.Iranian journal of public health · 2019Review
- Drug-induced prolonged corrected QT interval in patients with methadone and opium overdose.Substance abuse treatment, prevention, and policy · 2019Article
- Coronary Artery Bypass Graft Surgery Outcomes Following 6.5 Years: A Nested Case-control Study.International journal of preventive medicine · 2017Article
- Outcomes and long-term survival of coronary artery surgery: The controversial role of opium as risk marker.World journal of cardiology · 2016Article
- The Impact of Opium Consumption on Blood Glucose, Serum Lipids and Blood Pressure, and Related Mechanisms.Frontiers in physiology · 2016Review
- The effect of reciting the word "allah" on pain severity after coronary artery bypass graft surgery: a randomized clinical trial study in iran.Anesthesiology and pain medicine · 2014Article
- Effect of intravenous patient controlled ketamine analgesiaon postoperative pain in opium abusers.Anesthesiology and pain medicine · 2014Article
- Pain location and intensity during the first week following coronary artery bypass graft surgery.Anesthesiology and pain medicine · 2014Article
- Effects of clonidine premedication upon postoperative shivering and recovery time in patients with and without opium addiction after elective leg fracture surgeries.Anesthesiology and pain medicine · 2013Article
- Opium and cardiovascular health: A devil or an angel?Indian heart journalReview
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Authors and funding
2 authors.
Funding
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Abstract
backgroundOpium is a unique substance, regarding its analgesic effects. This may change the deteriorating effects of coronary artery disease (CAD) on quality of life (QOL) in addicted patients.
objectivesWe studied the QOL in opium-addicted and non-addicted CAD patients so as to determine the relationship between CAD risk factors and the subscales of their QOL. PATIENTS AND
methodsDemographic and laboratory data as well as coronary artery risk factors were obtained and SF-36 questionnaire was completed through interviews with 268 (38 opium-addicted and 230 non-addicted) patients with CAD who were candidates for isolated coronary artery bypass at Tehran Heart Center.
resultsMean Euro SCORE in addicted and non-addicted patients were 3.7 ± 7.6 and 2.4 ± 2.2 respectively (P = 0.036). In addicted group, higher preoperative HbA1c was associated with low physical function score (β = -0.395, P = 0.021). Low ejection fraction could negatively affect the general health (β = 0.394, P = 0.014) and mental health (β = 0.292, P = 0.015) subscales in the addicted group.
conclusionsDespite higher rate of morbidities in opium-addicted patients compared to non-addicted ones, subscales of QOL were similar between the two groups. High preoperative HbA1c and low ejection fraction appeared to be determinants of poor QOL in the opium-addicted patients.
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