ReviewEvidence-based complementary and alternative medicine : eCAM2013
Systematic reviews and meta-analyses of traditional chinese medicine must search chinese databases to reduce language bias.
Review in Evidence-based complementary and alternative medicine : eCAM, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 12 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed, 12 syntheses or guidelines pooled it, 50 citations in OpenAlex.
- Oral Chinese herbal formulas for premature ovarian insufficiency: a systematic review, meta-analysis, and exploratory therapeutic-principle subgroup analysis.Frontiers in endocrinology · 2026Pooled it
- "Cyclist at 12 o'clock!": a systematic review of in-vehicle advanced driver assistance systems (ADAS) for preventing car-rider crashes.Frontiers in public health · 2024Pooled it
- Methodological quality of systematic reviews on Chinese herbal medicine: a methodological survey.BMC complementary medicine and therapies · 2022Pooled it
- A multiyear systematic survey of the quality of reporting for randomised trials in dentistry, neurology and geriatrics published in journals of Spain and Latin America.BMC medical research methodology · 2021Pooled it
- The prevalence of and factors associated with inclusion of non-English language studies in Campbell systematic reviews: a survey and meta-epidemiological study.Systematic reviews · 2018Pooled it
- Pooled it
- The efficacy and safety of autologous blood transfusion drainage in patients undergoing total knee arthroplasty: a meta-analysis of 16 randomized controlled trials.BMC musculoskeletal disorders · 2016Pooled it
- Chinese Herbal Medicine and Fluorouracil-Based Chemotherapy for Colorectal Cancer: A Quality-Adjusted Meta-Analysis of Randomized Controlled Trials.Integrative cancer therapies · 2016Pooled it
- Effectiveness of acupuncture and related therapies for palliative care of cancer: overview of systematic reviews.Scientific reports · 2015Pooled it
- Tong-xin-luo capsule for patients with coronary heart disease after percutaneous coronary intervention.The Cochrane database of systematic reviews · 2015Pooled it
- Massage therapy for essential hypertension: a systematic review.Journal of human hypertension · 2015Pooled it
- Qigong for hypertension: a systematic review.Medicine · 2015Pooled it
- The optimal approach for retrieving systematic reviews was achieved when searching MEDLINE and Epistemonikos in addition to reference checking: a methodological validation study.BMC medical research methodology · 2024Article
- A comprehensive search string informed by an operational definition of complementary, alternative, and integrative medicine for systematic bibliographic database search strategies.BMC complementary medicine and therapies · 2022Article
- Operational definition of complementary, alternative, and integrative medicine derived from a systematic search.BMC complementary medicine and therapies · 2022Article
- Low methodological quality of systematic reviews on acupuncture: a cross-sectional study.BMC medical research methodology · 2021Article
- Choose your shortcuts wisely: COVID-19 rapid reviews of traditional, complementary and integrative medicine.Integrative medicine research · 2020Review
- Kaji-Ichigoside F1 and Rosamultin Protect Vascular Endothelial Cells against Hypoxia-Induced Apoptosis via the PI3K/AKT or ERK1/2 Signaling Pathway.Oxidative medicine and cellular longevity · 2020Article
- Barriers to the registration and conduct of Cochrane systematic reviews of traditional East Asian medicine therapies.European journal of integrative medicine · 2019Article
- Reporting items for systematic reviews and meta-analyses of acupuncture: the PRISMA for acupuncture checklist.BMC complementary and alternative medicine · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Systematic reviews (SRs) that fail to search non-English databases may miss relevant studies and cause selection bias. The bias may be particularly severe in SRs of traditional Chinese medicine (TCM) as most randomized controlled trials (RCT) in TCM are published and accessible only in Chinese. In this study we investigated how often Chinese databases were not searched in SRs of TCM, how many trials were missed, and whether a bias may occur if Chinese databases were not searched. We searched 5 databases in English and 3 in Chinese for RCTs of Chinese herbal medicine for coronary artery disease and found that 96.64% (115/119) eligible studies could be identified only from Chinese databases. In a random sample of 80 Cochrane reviews on TCM, we found that Chinese databases were only searched in 43 or 53.75%, in which almost all the included studies were identified from Chinese databases. We also compared SRs of the same topic and found that they may draw a different conclusion if Chinese databases were not searched. In conclusion, an overwhelmingly high percentage of eligible trials on TCM could only be identified in Chinese databases. Reviewers in TCM are suggested to search Chinese databases to reduce potential selection bias.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.