ReviewDeutsches Arzteblatt international2013
Control of the spread of vancomycin-resistant enterococci in hospitals: epidemiology and clinical relevance.
Review in Deutsches Arzteblatt international, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
30 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Global Prevalence of Vancomycin-Resistant Enterococcus faecium and Enterococcus faecalis Isolated From Clinical and Environmental Sources: A Systematic Review and Meta-Analysis.MicrobiologyOpen · 2026Pooled it
- Chemoproteomic profiling of adaptive ATP-binding protein activity inFEMS microbes · 2026Article
- Risk factors for vancomycin resistance in patients withMicrobiology spectrum · 2025Article
- Infection prevention and control without borders: comparison of guidelines on multidrug-resistant organisms in the northern Dutch-German cross-border region.Antimicrobial resistance and infection control · 2025Article
- Genomic Characterization of a Vancomycin-Resistant Strain ofInfection and drug resistance · 2023Article
- High adherence to national IPC guidelines as key to sustainable VRE control in Swiss hospitals: a cross-sectional survey.Antimicrobial resistance and infection control · 2022Article
- Spatiotemporal prediction of vancomycin-resistant Enterococcus colonisation.BMC infectious diseases · 2022Article
- Multiresistant Bacteria Isolated from Intestinal Faeces of Farm Animals in Austria.Antibiotics (Basel, Switzerland) · 2021Article
- Intestinal carriage of vancomycin-resistant Enterococcus spp. among high-risk patients in university hospitals in Serbia: first surveillance report.Annals of clinical microbiology and antimicrobials · 2021Article
- Prevalence and risk factors of colonisation with vancomycin-resistant Enterococci faecium upon admission to Germany's largest university hospital.GMS hygiene and infection control · 2021Article
- Ability of chlorhexidine, octenidine, polyhexanide and chloroxylenol to inhibit metabolism of biofilm-forming clinical multidrug-resistant organisms.Journal of infection prevention · 2021Article
- Multidrug Resistance (MDR) and Collateral Sensitivity in Bacteria, with Special Attention to Genetic and Evolutionary Aspects and to the Perspectives of Antimicrobial Peptides-A Review.Pathogens (Basel, Switzerland) · 2020Review
- The Characterization ofOpen medicine (Warsaw, Poland) · 2020Article
- Evaluation of Quadruple Real-Time PCR Method to Detect Enterococci Carrying Vancomycin-Resistant GenesFrontiers in medicine · 2020Article
- Near-ubiquitous presence of a vancomycin-resistantAntimicrobial resistance and infection control · 2019Article
- Engineered E. coli Nissle 1917 for the reduction of vancomycin-resistantBioengineering & translational medicine · 2018Article
- Multiresistant Bacteria Isolated from Activated Sludge in Austria.International journal of environmental research and public health · 2018Article
- Findings from an outbreak of carbapenem-resistant Klebsiella pneumoniae emphasize the role of antibiotic treatment for cross transmission.Infection · 2018Article
- Virulence Determinants and Antimicrobial Resistance Patterns of Vancomycin-resistantIranian journal of public health · 2018Article
- Economic burden of nosocomial infections caused by vancomycin-resistant enterococci.Antimicrobial resistance and infection control · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe spread of vancomycin-resistant enterococci (VRE), particularly E. faecium, in hospitals leads to many cases of colonization, but only sporadic infections. Detailed and valid risk assessment is needed so that patients at risk can be protected from VRE infection. The principal aims of risk assessment must include not only lowering VRE-associated morbidity and mortality in patients at risk, but also refraining from unnecessary anti-infective measures among those who are not at risk.
methodsWe selectively searched the PubMed database for pertinent articles on the epidemiology and clinical relevance of VRE in order to derive a uniform and practical hygiene strategy from the available scientific evidence.
resultsOnly low-level evidence is available for the interventions studied to date, and most of the recommendations that have been issued can be characterized as expert opinion. As a rule, VRE are not highly pathogenic; they tend to have high rates of colonization, but low rates of infection. The risk factors for colonization with VRE include (among others) the administration of antibiotics and immunosuppressants, prior hospitalization, diarrhea, intubation, and other invasive treatments. The areas of highest risk are hematology/oncology wards, liver transplantation wards, dialysis units, and neonatology wards.
conclusionThe chain of infection can be broken by improved and consistently applied standard hygienic measures (hand and surface disinfection). Some patients are nonetheless at elevated risk of VRE infection. In specific clinical situations, the optimal protection of these patients against VRE infection demands the obligatory enforcement of stricter hygienic measures (contact isolation).
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