SynthesisThe Cochrane database of systematic reviews2013
Fetal and umbilical Doppler ultrasound in high-risk pregnancies.
Synthesis in The Cochrane database of systematic reviews, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03584763 (Frequency of Performing Umbilical Artery Doppler in the Third Trimester in High Risk Pregnancy A Randomized Controlled Trial), which is not on this map. Cited by 50 papers, 10 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Frequency of Performing Umbilical Artery Doppler in the Third Trimester in High Risk Pregnancy A Randomized Controlled Trial
Who cites it
50 citing papers in PubMed, 10 syntheses or guidelines pooled it, 434 citations in OpenAlex.
- Prognostic accuracy of cerebroplacental ratio and middle cerebral artery Doppler for adverse perinatal outcome: systematic review and meta-analysis.Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology · 2018Pooled it
- Fetal and umbilical Doppler ultrasound in high-risk pregnancies.The Cochrane database of systematic reviews · 2017Pooled it
- EULAR recommendations for women's health and the management of family planning, assisted reproduction, pregnancy and menopause in patients with systemic lupus erythematosus and/or antiphospholipid syndrome.Annals of the rheumatic diseases · 2017Guideline
- Cardiotocography versus intermittent auscultation of fetal heart on admission to labour ward for assessment of fetal wellbeing.The Cochrane database of systematic reviews · 2017Pooled it
- Immediate versus deferred delivery of the preterm baby with suspected fetal compromise for improving outcomes.The Cochrane database of systematic reviews · 2016Pooled it
- Use of biochemical tests of placental function for improving pregnancy outcome.The Cochrane database of systematic reviews · 2015Pooled it
- Planned early delivery versus expectant management of the term suspected compromised baby for improving outcomes.The Cochrane database of systematic reviews · 2015Pooled it
- Antenatal cardiotocography for fetal assessment.The Cochrane database of systematic reviews · 2015Pooled it
- Fetal and umbilical Doppler ultrasound in normal pregnancy.The Cochrane database of systematic reviews · 2015Pooled it
- Admission tests other than cardiotocography for fetal assessment during labour.The Cochrane database of systematic reviews · 2011Pooled it
- Routine antenatal ultrasound in low- and middle-income countries: first look - a cluster randomised trial.BJOG : an international journal of obstetrics and gynaecology · 2018Trial
- Adherence to medical recommendations in high-risk pregnancy: dispositional and situational predictors with a focus on emotional reactivity.CNS spectrums · 2025Article
- Exposure to Extreme Heat Increases Preterm Birth Risk: Hypothetical Pathophysiological Mechanisms.BioEssays : news and reviews in molecular, cellular and developmental biology · 2025Review
- Maternal plasma syndecan-1: a biomarker for fetal growth restriction.The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians · 2023Article
- The effects of aging and gestational month on uteroplacental vascular perfusion, and umbilical artery hemodynamics in pregnant jennies.BMC veterinary research · 2022Article
- Systematic review evaluating the efficacy of the cerebroplacental ratio (CPR) in saving babies lives.Ultrasound (Leeds, England) · 2022Review
- Article
- Impact of umbilical cord length on fetal circulatory system by Doppler assessment.Journal of ultrasound · 2020Observational
- Idiopathic Normal Pressure Hydrocephalus - What We Know.Maedica · 2019Article
- Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAbnormal blood flow patterns in fetal circulation detected by Doppler ultrasound may indicate poor fetal prognosis. It is also possible false positive Doppler ultrasound findings could encourage inappropriate early delivery.
objectivesThe objective of this review was to assess the effects of Doppler ultrasound used to assess fetal well-being in high-risk pregnancies on obstetric care and fetal outcomes. SEARCH
methodsWe updated the search of the Cochrane Pregnancy and Childbirth Group's Trials Register on 30 September 2013. SELECTION CRITERIA: Randomised and quasi-randomised controlled trials of Doppler ultrasound for the investigation of umbilical and fetal vessels waveforms in high-risk pregnancies compared with no Doppler ultrasound. DATA COLLECTION AND ANALYSIS: Two review authors independently assessed the studies for inclusion, assessed risk of bias and carried out data extraction. Data entry was checked. MAIN
resultsEighteen completed studies involving just over 10,000 women were included. The trials were generally of unclear quality with some evidence of possible publication bias. The use of Doppler ultrasound in high-risk pregnancy was associated with a reduction in perinatal deaths (risk ratio (RR) 0.71, 95% confidence interval (CI) 0.52 to 0.98, 16 studies, 10,225 babies, 1.2% versus 1.7 %, number needed to treat (NNT) = 203; 95% CI 103 to 4352). There were also fewer inductions of labour (average RR 0.89, 95% CI 0.80 to 0.99, 10 studies, 5633 women, random-effects) and fewer caesarean sections (RR 0.90, 95% CI 0.84 to 0.97, 14 studies, 7918 women). No difference was found in operative vaginal births (RR 0.95, 95% CI 0.80 to 1.14, four studies, 2813 women), nor in Apgar scores less than seven at five minutes (RR 0.92, 95% CI 0.69 to 1.24, seven studies, 6321 babies). AUTHORS'
conclusionsCurrent evidence suggests that the use of Doppler ultrasound in high-risk pregnancies reduced the risk of perinatal deaths and resulted in less obstetric interventions. The quality of the current evidence was not of high quality, therefore, the results should be interpreted with some caution. Studies of high quality with follow-up studies on neurological development are needed.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.