Evidence map›Paper›PMID 24222315›Full record

ArticleCurrent treatment options in neurology2013

Treatment of dementia with lewy bodies.

Brendon P Boot, Eric M McDade, Scott M McGinnis, Bradley F Boeve

Open access · greenAbstract read
In one paragraph

Article in Current treatment options in neurology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 44 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Review
  6. Case Study 3: A 58-Year-Old Woman Referred for Evaluation of Suspected Alzheimer Dementia.The Journal of neuropsychiatry and clinical neurosciences · 2022
    Article
  7. Review
  8. Coping with Dementia in the Middle of the COVID-19 Pandemic.Journal of Korean medical science · 2020
    Review
  9. Article
  10. Review
  11. Review
  12. Article
  13. Dementia With Lew Body: Impacts of Surgery.American journal of Alzheimer's disease and other dementias · 2016
    Review
  14. Lewy body dementias.Lancet (London, England) · 2015
    Review
  15. Comprehensive treatment of dementia with Lewy bodies.Alzheimer's research & therapy · 2015
    Article
  16. Review
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Brendon P BootDepartment of Neurology, Brigham and Women's Hospital, 221 Longwood Ave, Boston, MA, 02115, USA, bboot@partners.org.
Eric M McDade
Scott M McGinnis
Bradley F Boeve
Brigham and Women's Hospital · USMayo Clinic in Arizona · USUniversity of Pittsburgh Medical Center · US

Funding

Vascular factors, physical activity, and inflammation as modulators of neurodegenerative and cognitive trajectories (Project 2)P01AG036694 · NIA · MASSACHUSETTS GENERAL HOSPITAL · PI Rebecca E Amariglio · 2010 to 2026
$50.2M
SUPPLEMENT TO ALZHEIMERS DISEASE PATIENT REGISTRYU01AG006786 · NIA · MAYO CLINIC ROCHESTER · PI GRAFF-RADFORD, JONATHAN, JACK, CLIFFORD R. · 1986 to 2023
$49.6M
THE ROLE OF ADVANCED CAA IN ALZHEIMER'S DEMENTIAP50AG005134 · NIA · MASSACHUSETTS GENERAL HOSPITAL · PI HYMAN, BRADLEY T. · 1985 to 2018
$42.1M
THE PGRN/TDP-43 AXIS IN ALZHEIMER?S DISEASE AND NEURODEGENERATIONP50AG016574 · NIA · MAYO CLINIC ROCHESTER · PI BU, GUOJUN · 1999 to 2018
$36.9M
The Frontotemporal Lobar Degeneration Neuroimaging InitiativeR01AG032306 · NIA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI ROSEN, HOWARD J · 2009 to 2013
$10.0M
Epidemiology of Familial Late-Onset Alzheimer's DiseaseR01AG041797 · NIA · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI MAYEUX, RICHARD P · 2012 to 2016
$4.2M
NIA NIH HHS P01 AG036694NIA NIH HHS P50 AG005134NIA NIH HHS P50 AG016574NIA NIH HHS R01 AG032306NIA NIH HHS R01 AG041797NIA NIH HHS U01 AG006786
6 · The paper itself

Abstract

opinion statementDementia with Lewy bodies (DLB) is a multisystem disorder with diverse disease expression. A treatment regime restricted to the cognitive aspects of the disease does no favor to patients. Instead, patients should be educated to recognize the symptoms of this multisystem involvement. There are no treatments that slow the progression of disease, but symptomatic treatments can be effective. When thinking about treatment, we find it useful to divide the symptoms and signs into five categories: (a) cognitive features, (b) neuropsychiatric features, (c) motor dysfunction, (d) autonomic dysfunction, and (e) sleep dysfunction. Clinicians, funding bodies and industry are increasingly recognizing the importance of this common and debilitating disease.

Identifiers

PMID24222315
PMCPMC3913181
OpenAlexW2023035068

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.