Trial reportCancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology2014
Psychological distress after a positive fecal occult blood test result among members of an integrated healthcare delivery system.
Trial report in Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 2 of them syntheses that pooled it.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
22 citing papers in PubMed, 2 syntheses or guidelines pooled it, 38 citations in OpenAlex.
- Pooled it
- Pooled it
- Hepatocellular carcinoma surveillance may be associated with potential psychological harms in patients with cirrhosis.Hepatology (Baltimore, Md.) · 2024Trial
- Psychological effects of colorectal cancer screening: ParticipantsWorld journal of gastroenterology · 2016Trial
- Do no harm: no psychological harm from colorectal cancer screening.British journal of cancer · 2016Trial
- European Code Against Cancer, 5th edition - organised cancer screening programmes.Molecular oncology · 2026Review
- Factors associated with false fecal immunochemical test results in colorectal cancer screening.World journal of gastrointestinal oncology · 2025Article
- Health utility assessments in individuals undergoing diagnostic and surveillance colonoscopy: improved discrimination with a cancer-specific scale.Cancer causes & control : CCC · 2024Article
- Methodological Quality of PROMs in Psychosocial Consequences of Colorectal Cancer Screening: A Systematic Review.Patient related outcome measures · 2023Review
- Comorbidities and Risk Factors of Patients Diagnosed with CRC after Positive Fecal Test in Real Life.Cancers · 2022Article
- Depression and Anxiety Are Common Among Patients With Cirrhosis.Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association · 2022Article
- The clinical utility of a comprehensive psychosomatic assessment in the program for colorectal cancer prevention: a cross-sectional study.Scientific reports · 2021Article
- Barriers to completing colonoscopy after a positive fecal occult blood test.Israel journal of health policy research · 2021Article
- Proton-pump inhibitors are associated with a high false-positivity rate in faecal immunochemical testing.Journal of gastroenterology · 2021Article
- Repeated Automated Mobile Text Messaging Reminders for Follow-Up of Positive Fecal Occult Blood Tests: Randomized Controlled Trial.JMIR mHealth and uHealth · 2019Article
- Reasons For Lack of Follow-up Colonoscopy Among Persons With A Positive Fecal Occult Blood Test Result: A Qualitative Study.The American journal of gastroenterology · 2018Article
- Psychosocial consequences of skin cancer screening.Preventive medicine reports · 2018Article
- The IARC Perspective on Colorectal Cancer Screening.The New England journal of medicine · 2018Article
- Primary care visit use after positive fecal immunochemical test for colorectal cancer screening.Cancer · 2017Article
- Population screening for BRCA1/BRCA2 mutations: lessons from qualitative analysis of the screening experience.Genetics in medicine : official journal of the American College of Medical Genetics · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 3 institutions in 1 country.
Funding
Abstract
backgroundColorectal cancer screening (CRCS) reduces morbidity and mortality; however, the positive benefits might be partially offset by long-term distress following positive screening results. We examined relationships among colorectal cancer-specific worry and situational anxiety after positive fecal occult blood tests [FOBT (+)] compared with receipt of negative results.
methodsOf note, 2,260 eligible members of Group Health, an integrated healthcare delivery system, completed baseline surveys and received FOBT screening kits, with 1,467 members returning the kits. We matched FOBT (+) patients (n = 55) 1:2 on age and sex with FOBT (-) respondents (n = 110). Both groups completed follow-up surveys at 7 to 14 days and 4 months after screening. We assessed situational anxiety (State-Trait Anxiety Inventory, STAI), colorectal cancer worry frequency, and mood disturbance.
resultsMean age was 59 years, and majority were women (62%) and White (89%). After adjusting for age, sex, and baseline worry, at 7 to 14 days after screening, the FOBT (+) group was 3.82 [95% confidence interval (CI), 1.09-13.43] times more likely to report colorectal cancer-related mood disturbances and significantly higher mean STAI scores than the FOBT (-) group (mean = 38.8 vs. 30.9; P = 0.007). At 4-month posttest, mood disturbances and situational anxiety seemed to drop to baseline levels for FOBT (+). No colon cancer worry frequency was observed.
conclusionsFOBT (+) results are associated with short-term situational anxiety and colorectal cancer-specific mood disturbances. IMPACT: Distress from FOBT (+) results declined to near-baseline levels by 4 months. Additional studies are needed to clarify the relationship between long-term distress and follow-up colonoscopy.
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