ArticleEuropean radiology2014
Median nerve stiffness measurement by shear wave elastography: a potential sonographic method in the diagnosis of carpal tunnel syndrome.
Article in European radiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03970408 (Effect of Neck Movements on Median Nerve Longitudinal Excursion During Neurodynamic Mobilization in Patients With Carpal Tunnel Syndrome), which is not on this map. Cited by 75 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effect of Neck Movements on Median Nerve Longitudinal Excursion During Neurodynamic Mobilization in Patients With Carpal Tunnel Syndrome
Who cites it
75 citing papers in PubMed, 192 citations in OpenAlex.
- Dynamic Changes in Peripheral Nerve Stiffness After Regional Anesthesia: Implications of Shear Wave Elastography in Adductor Canal Block.Journal of clinical medicine · 2026Review
- Shear Wave Elastography of the Brachial Plexus and Target Muscle in Interscalene Block: A Narrative Review of Quantitative Tools for Patient-Centered Regional Anesthesia.Journal of clinical medicine · 2026Review
- Ultrasound strain elastography for peripheral nerves localization for regional anesthesia A prospective observational pilot study.Journal of clinical monitoring and computing · 2026Observational
- Investigation of perioperative changes in sciatic nerve stiffness in patients with lumbar disc herniation using shear wave elastography: A longitudinal cohort study.Fukushima journal of medical science · 2026Article
- Radiation-Induced Brachial Plexopathy: Current Understanding, Diagnosis, and Treatment Options.Journal of hand surgery global online · 2026Review
- Treatment Monitoring of Carpal Tunnel Syndrome Using Shear Wave Elastography: A Pilot In Vivo Study.Cureus · 2026Article
- Emergent technologies in clinical neurophysiology to study the neuromuscular system: IFCN handbook chapter.Clinical neurophysiology practice · 2026Review
- Shear Wave Elastography of the Sciatic Nerve and Its Relationship with Posterior Chain Flexibility in Healthy Participants: An Observational Study.Sensors (Basel, Switzerland) · 2025Observational
- Lesion Classification by Model-Based Feature Extraction: A Differential Affine Invariant Model of Soft Tissue Elasticity in CT Images.Journal of imaging informatics in medicine · 2025Article
- The Median Nerve Displays Adaptive Characteristics When Exposed to Repeated Pinch Grip Efforts of Varying Rates of Force Development: An Ultrasonic Investigation.Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine · 2025Article
- Diagnostic cut-off values and grading of carpal tunnel syndrome by shear wave elastography at different tunnel locations correlated with gold standard nerve conduction study - a case-control study.Journal of ultrasonography · 2025Article
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- Diagnostic efficacy of high-frequency Grey-scale ultrasonography and Sono-elastography in grading the severity of carpal tunnel syndrome in comparison to nerve conduction studies.Skeletal radiology · 2024Article
- Changes in Ultrasound Parameters of the Median Nerve at Different Positions of the Radiocarpal Joint in Patients with Carpal Tunnel Syndrome.Sensors (Basel, Switzerland) · 2024Article
- Shear wave elastography of transverse carpal ligament increased with simulated carpal tunnel pressure.Journal of orthopaedic surgery and research · 2024Article
- Using ultrasound shear wave elastography to characterize peripheral nerve mechanics: a systematic review on the normative reference values in healthy individuals.Ultrasonography (Seoul, Korea) · 2024Article
- Utility of shear wave elastography for diagnosing carpal tunnel syndrome with psoriatic arthritis.Irish journal of medical science · 2024Article
- Elastography of nerves in the wrists of cyclists.Polish journal of radiology · 2024Article
- Diagnostic Accuracy of Integrating Ultrasound and Shear Wave Elastography in Assessing Carpal Tunnel Syndrome Severity: a Prospective Observational Study.Orthopedic research and reviews · 2024Article
15 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
10 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo measure the median nerve (MN) stiffness by quantitative shear wave elastography (SWE) at the carpal tunnel inlet and to determine whether SWE can be used in the diagnosis of carpal tunnel syndrome (CTS).
methodsThe study included 37 consecutive patients (60 wrists) with a definitive diagnosis of CTS and 18 healthy volunteers (36 wrists). The MN cross-sectional area (CSA) by ultrasound and stiffness by SWE were studied. The difference between CTS patients and controls, and the difference among subgroups based on electrodiagnostic tests were studied by the Student's t test. Interobserver variability and ROC analysis were performed.
resultsThe MN stiffness was significantly higher in the CTS group (66.7 kPa) when compared to controls (32.0 kPa) (P < 0.001), and higher in the severe or extreme severity group (101.4 kPa) than the mild or moderate severity group (55.1 kPa) (P < 0.001). A 40.4-kPa cut-off value on SWE revealed sensitivity, specificity, PPV, NPV and accuracy of 93.3%, 88.9%, 93.3%, 88.9% and 91.7%, respectively. Interobserver agreement was excellent for SWE measurements.
conclusionsMedian nerve stiffness at the carpal tunnel inlet is significantly higher in patients with carpal tunnel syndrome, for whom shear wave elastography appears to be a highly reproducible diagnostic technique. KEY POINTS: • Clinical examination is important for diagnosis of carpal tunnel syndrome • Shear wave elastography (SWE) offers new clinical opportunities within diagnostic ultrasound • SWE is highly reproducible in evaluation of median nerve stiffness • Median nerve stiffness is significantly increased in carpal tunnel syndrome • Elastography could become useful in diagnosis of carpal tunnel syndrome.
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