ArticleNeuroImage2014
White matter microstructure changes induced by motor skill learning utilizing a body machine interface.
Article in NeuroImage, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
27 citing papers in PubMed.
- Trial
- Changes of Brain Connectivity in the Primary Motor Cortex After Subcortical Stroke: A Multimodal Magnetic Resonance Imaging Study.Medicine · 2016Trial
- Exercise-induced brain changes in cannabis use disorder: a longitudinal MRI study of a 12-week supervised HIIT program.Molecular psychiatry · 2026Article
- Transient effects in corticospinal and reticulospinal tract excitability induced by motor skill and isometric resistance training.Brain research · 2026Article
- Alterations of static and dynamic changes in intrinsic brain activity and its relation to behavioral outcomes in subcortical ischemic stroke after one-month intervention.Scientific reports · 2025Article
- Neurorehabilitation and white matter repair in traumatic spinal cord injury: a dialogue between clinical and preclinical studies.Frontiers in neurology · 2025Review
- Associating white matter microstructural integrity and improvements in reactive stepping in people with Parkinson's Disease.Brain imaging and behavior · 2024Article
- Neural bases characterizing chronic and severe upper-limb motor deficits after brain lesion.Journal of neural transmission (Vienna, Austria : 1996) · 2023Article
- The influence of NRXN1 on systemizing and the brain structure in healthy adults.Brain imaging and behavior · 2022Article
- Rapid microstructural plasticity in the cortical semantic network following a short language learning session.PLoS biology · 2021Article
- Resection of cerebellar tumours causes widespread and functionally relevant white matter impairments.Human brain mapping · 2021Article
- Structural and functional brain signatures of endurance runners.Brain structure & function · 2021Article
- White Matter Neuroplasticity: Motor Learning Activates the Internal Capsule and Reduces Hemodynamic Response Variability.Frontiers in human neuroscience · 2020Article
- Fitness Level Influences White Matter Microstructure in Postmenopausal Women.Frontiers in aging neuroscience · 2020Article
- Microstructural integrity of corticospinal and medial lemniscus tracts: insights from diffusion tensor tractography of right-hand amputees.Journal of neurophysiology · 2019Article
- Functional Alignment with Anatomical Networks is Associated with Cognitive Flexibility.Nature human behaviour · 2018Article
- Diffusion tensor MRI tractography reveals increased fractional anisotropy (FA) in arcuate fasciculus following music-cued motor training.Brain and cognition · 2017Article
- White Matter Microstructural Changes Following Quadrato Motor Training: A Longitudinal Study.Frontiers in human neuroscience · 2017Article
- Body-Machine Interfaces after Spinal Cord Injury: Rehabilitation and Brain Plasticity.Brain sciences · 2016Article
- Disrupted mitochondrial genes and inflammation following stroke.Life sciences · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
The purpose of this study is to identify white matter microstructure changes following bilateral upper extremity motor skill training to increase our understanding of learning-induced structural plasticity and enhance clinical strategies in physical rehabilitation. Eleven healthy subjects performed two visuo-spatial motor training tasks over 9 sessions (2-3 sessions per week). Subjects controlled a cursor with bilateral simultaneous movements of the shoulders and upper arms using a body machine interface. Before the start and within 2days of the completion of training, whole brain diffusion tensor MR imaging data were acquired. Motor training increased fractional anisotropy (FA) values in the posterior and anterior limbs of the internal capsule, the corona radiata, and the body of the corpus callosum by 4.19% on average indicating white matter microstructure changes induced by activity-dependent modulation of axon number, axon diameter, or myelin thickness. These changes may underlie the functional reorganization associated with motor skill learning.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.