Evidence map›Paper›PMID 24219988›Full record

ArticleThe EMBO journal2013

Amphisomes: out of the autophagosome shadow?

Jana Sanchez-Wandelmer, Fulvio Reggiori

Open access · greenAbstract readComment
In one paragraph

Article in The EMBO journal, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 61 citations in OpenAlex.

  1. Article
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  6. Viruses and autophagy: bend, but don't break.Nature reviews. Microbiology · 2024
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  15. The S100A10-AnxA2 complex is associated with the exocytosis of hepatitis B virus in intrauterine infection.Laboratory investigation; a journal of technical methods and pathology · 2022
    Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Jana Sanchez-WandelmerDepartment of Cell Biology and Institute of Biomembranes, University Medical Centre Utrecht, Utrecht, The Netherlands.
Fulvio Reggiori
University Medical Center Utrecht · NLUtrecht University · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Amphisomes are intermediate organelles, formed during autophagy through the fusion between autophagosomes and endosomes. Complex multivesicular vacuoles that resemble amphisomes have been observed in various cell types, but whether they have cellular roles other than being a precursor structure is still enigmatic. While autophagy-related (ATG) proteins interact with the endocytic pathways in other processes different from autophagy, Patel and colleagues now report that these factors come together to generate amphisome-like compartments that regulate mucin secretion in goblet cells.

Indexed as

AutophagyAnimalsAutophagy-Related Protein 5Goblet CellsMicrotubule-Associated ProteinsReactive Oxygen SpeciesAtg5 protein, mouseAutophagy-Related Protein 5Map1lc3b protein, mouseMicrotubule-Associated ProteinsReactive Oxygen Species

Identifiers

PMID24219988
PMCPMC3981145
OpenAlexW1563735171

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.