Evidence map›Paper›PMID 24219831›Full record

ArticleJournal of agricultural and food chemistry2014

Comparative analysis of phenolic content and profile, antioxidant capacity, and anti-inflammatory bioactivity in wild Alaskan and commercial Vaccinium berries.

Mary H Grace, Debora Esposito, Kriya L Dunlap, Mary Ann Lila

Abstract readComparative Study
In one paragraph

Article in Journal of agricultural and food chemistry, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
54citing papers in PubMed, 1 pooled it
3.2field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

54 citing papers in PubMed, 1 synthesis or guideline pooled it, 151 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Review
  5. Article
  6. Alaska's Flora as a Treatment for Cancer.International journal of biopharmaceutical sciences · 2024
    Article
  7. Article
  8. Effects ofFrontiers in molecular biosciences · 2024
    Review
  9. Development of Spray DriedAntioxidants (Basel, Switzerland) · 2023
    Article
  10. Article
  11. Article
  12. Molecular Characterization ofInternational journal of molecular sciences · 2023
    Article
  13. Article
  14. Article
  15. Review
  16. Review
  17. Article
  18. Article
  19. Lingonberry (Frontiers in plant science · 2022
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Mary H GracePlants for Human Health Institute, Food Bioprocessing and Nutrition Sciences Department, North Carolina State University, North Carolina Research Campus , 600 Laureate Way, Kannapolis, North Carolina 28081, United States.
Debora Esposito
Kriya L Dunlap
Mary Ann Lila
North Carolina State University · USUniversity of Alaska Fairbanks · US

Funding

The Administrative CoreP20GM103395 · NIGMS · UNIVERSITY OF ALASKA FAIRBANKS · PI BRIAN M BARNES · 2012 to 2026
$66.1M
NIGMS NIH HHS P20 GM103395NIGMS NIH HHS P20GM103395
6 · The paper itself

Abstract

Wild Alaskan Vaccinium berries, V. vitis-idaea (lowbush cranberry) and V. uliginosum (bog blueberry), were investigated in parallel with their commercial berry counterparts, V. macrocarpon (cranberry) and V. angustifolium (lowbush blueberry). Lowbush cranberry accumulated about twice the total phenolics (624.4 mg/100 g FW) and proanthocyanidins (278.8 mg/100 g) content as commercial cranberries, but A-type proanthocyanidins were more prevalent in the latter. Bog blueberry anthocyanin and total phenolic contents of 220 and 504.5 mg/100 g, respectively, significantly exceeded those of the lowbush blueberry. Chlorogenic acid, however, was quite high in lowbush blueberry (83.1 mg/100 g), but undetected in bog blueberry, and the proanthocyanidins of lowbush blueberry had significantly higher levels of polymerization. Antioxidant capacity (DPPH, APTS, and FRAP) correlated with phenolic content for each berry. A polyphenol-rich fraction from lowbush cranberry exhibited dose-dependent inhibition of LPS-elicited induction of IL-1β in RAW 264.7 cells, indicative of strong anti-inflammatory activity. These results corroborate the historic use of wild Alaskan berries as medicinally important foods in Alaska Native communities.

Indexed as

AlaskaAnimalsAnti-Inflammatory AgentsAntioxidantsChromatography, High Pressure LiquidFruitMacrophagesMass SpectrometryMicePhenolsPlant ExtractsVacciniumAnti-Inflammatory AgentsAntioxidantsPhenolsPlant Extractsanti-inflammatoryantioxidantphenolicsVaccinium vitis-idaeaV. angustifoliumV. macrocarponV. uliginosum

Identifiers

PMID24219831
PMCPMC4026347
OpenAlexW2333970113

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.