SynthesisWorld journal of surgical oncology2013
Clinical characteristics and prognosis of primary leiomyosarcoma of the pancreas: a systematic review.
Synthesis in World journal of surgical oncology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed.
- Pancreatic Tail Leiomyosarcoma With Hepatic Metastases: Diagnostic and Therapeutic Challenges: A Case Report.Clinical medicine insights. Case reports · 2026Article
- OncoImmune machine-learning model predicts immune response and prognosis in leiomyosarcoma.Biomolecules & biomedicine · 2025Article
- Rare Solid Pancreatic Lesions on Cross-Sectional Imaging.Diagnostics (Basel, Switzerland) · 2023Review
- Leiomyosarcoma, a rare smooth muscle cancer in the pancreas: An adjuvant radiotherapy treatment approach.Cancer reports (Hoboken, N.J.) · 2023Article
- Undifferentiated pleomorphic sarcoma of the pancreas: a rare case report and literature review.World journal of surgical oncology · 2022Review
- Primary Pancreatic Leiomyosarcoma: A Rare Malignant Transformation of Primary Pancreatic Head Leiomyoma.Cureus · 2021Article
- Successful treatment of advanced pancreatic leiomyosarcoma treated with gemcitabine plusInternational cancer conference journal · 2021Article
- Pancreatic leiomyosarcoma: a diagnostic challenge and literature review.BMJ case reports · 2019Review
- Irreversible electroporation in a case of pancreatic leiomyosarcoma: a novel weapon versus a rare malignancy?World journal of surgical oncology · 2019Article
- Leiomyosarcoma Involving the Pancreas Diagnosed by Endoscopic Ultrasound Fine-Needle Aspiration.Journal of gastrointestinal cancer · 2018Article
- A case report of primary pancreatic leiomyosarcoma requiring six additional resections for recurrences.International journal of surgery case reports · 2017Article
- Transdifferentiation of pancreatic stromal tumor into leiomyosarcoma with metastases to liver and peritoneum: a case report.BMC cancer · 2016Article
- Primary Leiomyosarcoma of the Pancreas-a Case Report and a Comprehensive Review.Journal of gastrointestinal cancer · 2016Review
- RRM1, ERCC1 and TS1 Immunofluorescence Expression in Leiomyosarcoma: A Tissue Microarray Study with Clinical Outcome Correlation Analysis.Pathology oncology research : POR · 2016Article
- Primary leiomyosarcoma of the pancreas: report of a case treated by local excision and review of the literature.Surgical case reports · 2015Article
- Pancreatic leiomyosarcoma in a domestic shorthair cat.JFMS open reportsArticle
- Review
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5 authors.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundPrimary pancreatic leiomyosarcoma (PLMS) is rare. The clinical characteristics and prognosis is still not completely understood. The aim of the present study is to identify the clinical characteristics and long-term outcomes of PLMS from the existing reported cases in different scientific literature.
methodsPLMS cases reported in Chinese and English journals were collected and reviewed. Clinical features and long-term outcomes of these cases were summarized and analyzed statistically.
resultsA total of 69 cases reported from both Chinese and English journals were included in the present study. An equal incidence in gender was observed. The mean age was 53.9 ± 14.7 years. The most common symptoms were abdominal mass, abdominal pain, and weight loss. The mean size of the tumor was 11.4 ± 7.1 cm. The incidence of PLMS between the head and body-tail of the pancreas had a similar pattern. Twenty-five percent of patients had distant metastasis and 19% of patients had adjacent organs/vessels invasion at the time of diagnosis. But lymph node metastasis was documented in only one (1.5%) patient. The median survival time was 48 months. The overall 1-, 3-, 5-, and 10-year survival rates were 66.6%, 51.2%, 43.9%, and 29.3%, respectively. Results from the multivariate analysis showed that non-radical resection (P = 0.000; hazard ratio (HR) 5.128; 95% confidence interval (CI) 2.041-12.987) was the independent adverse prognostic factor. Adjacent organs/vessels invasion (yes) may be considered as an another potential independent adverse prognostic factor (P = 0.071; HR 2.708; 95% CI 0.981-7.474).
conclusionsPLMS is rare without specific clinical features. PLMS is an aggressive tumor and has a poor prognosis. Radical resection can prolong survival time of the patients.
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