ArticleBMC genomics2013
Comparative genomics reveals candidate carotenoid pathway regulators of ripening watermelon fruit.
Article in BMC genomics, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers.
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Who cites it
46 citing papers in PubMed, 106 citations in OpenAlex.
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- Comprehensive Characterization of B-Box Zinc Finger Genes inPlants (Basel, Switzerland) · 2023Article
- Identification of a novel locusFrontiers in genetics · 2023Article
- Genetic mapping of a single nuclear locus determines the white flesh color in watermelon (Frontiers in plant science · 2023Article
- Putative Transcription Factor Genes Associated with Regulation of Carotenoid Biosynthesis in Chili Pepper Fruits Revealed by RNA-Seq Coexpression Analysis.International journal of molecular sciences · 2022Article
- Genome Sequencing of up to 6,000-Year-Old Citrullus Seeds Reveals Use of a Bitter-Fleshed Species Prior to Watermelon Domestication.Molecular biology and evolution · 2022Article
- ClZISO mutation leads to photosensitive flesh in watermelon.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2022Review
- Comparative transcriptomic analysis of two Cucumis melo var. saccharinus germplasms differing in fruit physical and chemical characteristics.BMC plant biology · 2022Article
- Comparison of Metabolome and Functional Properties of Three Korean Cucumber Cultivars.Frontiers in plant science · 2022Article
- Primary mapping of quantitative trait loci regulating multivariate horticultural phenotypes of watermelon (Frontiers in plant science · 2022Article
- Enhancement of violaxanthin accumulation inFrontiers in microbiology · 2022Article
- Genetic Analysis of Fruit Quality Traits in Sweet Watermelon (Frontiers in plant science · 2022Review
- Quantitative Transcriptomic and Proteomic Analysis of Fruit Development and Ripening in Watermelon (Frontiers in plant science · 2022Article
- Whole-Genome Resequencing of Near-Isogenic Lines Reveals a Genomic Region Associated with HighPlants (Basel, Switzerland) · 2021Article
- Transcriptional Regulation of Ripening in Chili Pepper Fruits (International journal of molecular sciences · 2021Review
- A chromosome-level genome of a Kordofan melon illuminates the origin of domesticated watermelons.Proceedings of the National Academy of Sciences of the United States of America · 2021Article
- Comparative Metabolomic Profiling ofMetabolites · 2021Article
- A Catalog of Natural Products Occurring in Watermelon-Frontiers in nutrition · 2021Article
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Authors and funding
8 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundMany fruits, including watermelon, are proficient in carotenoid accumulation during ripening. While most genes encoding steps in the carotenoid biosynthetic pathway have been cloned, few transcriptional regulators of these genes have been defined to date. Here we describe the identification of a set of putative carotenoid-related transcription factors resulting from fresh watermelon carotenoid and transcriptome analysis during fruit development and ripening. Our goal is to both clarify the expression profiles of carotenoid pathway genes and to identify candidate regulators and molecular targets for crop improvement.
resultsTotal carotenoids progressively increased during fruit ripening up to ~55 μg g(-1) fw in red-ripe fruits. Trans-lycopene was the carotenoid that contributed most to this increase. Many of the genes related to carotenoid metabolism displayed changing expression levels during fruit ripening generating a metabolic flux toward carotenoid synthesis. Constitutive low expression of lycopene cyclase genes resulted in lycopene accumulation. RNA-seq expression profiling of watermelon fruit development yielded a set of transcription factors whose expression was correlated with ripening and carotenoid accumulation. Nineteen putative transcription factor genes from watermelon and homologous to tomato carotenoid-associated genes were identified. Among these, six were differentially expressed in the flesh of both species during fruit development and ripening.
conclusionsTaken together the data suggest that, while the regulation of a common set of metabolic genes likely influences carotenoid synthesis and accumulation in watermelon and tomato fruits during development and ripening, specific and limiting regulators may differ between climacteric and non-climacteric fruits, possibly related to their differential susceptibility to and use of ethylene during ripening.
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