ArticleBMC health services research2013
Evaluating adverse drug event reporting in administrative data from emergency departments: a validation study.
Article in BMC health services research, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers, 4 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
46 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Incidence of and Risk Factors for Repeat Adverse Drug Events: A Systematic Review.Journal of patient safety · 2026Pooled it
- The prevalence of medication-related adverse events in inpatients-a systematic review and meta-analysis.European journal of clinical pharmacology · 2017Pooled it
- Racial and Ethnic Disparities in Adverse Drug Events: A Systematic Review of the Literature.Journal of racial and ethnic health disparities · 2015Pooled it
- ICD-10 codes used to identify adverse drug events in administrative data: a systematic review.Journal of the American Medical Informatics Association : JAMIAPooled it
- Impact of early in-hospital medication review by clinical pharmacists on health services utilization.PloS one · 2017Trial
- Comparative Effectiveness and Outcomes of Nebivolol Versus Other Beta Blockers in Patients With Hypertension: A Multicenter Cohort Study.Journal of the American Heart Association · 2026Article
- The use of international classification of diseases codes to identify hospital admissions linked with adverse drug events: Validation study.British journal of clinical pharmacology · 2025Article
- Assessing the safety and efficacy of prescribing psychologists in New Mexico and Louisiana.The American psychologist · 2025Article
- Characteristics of Drug-RElated Hospitalizations for Nursing HOme Residents: Cross-Sectional RENHO Study.Drug safety · 2025Article
- ICD-10 Codes to Identify Adverse Drug Events Associated with Antibiotics in Administrative Data.Antibiotics (Basel, Switzerland) · 2025Article
- Comparing the performance of multiple trigger tools in identifying medication-related hospital readmissions.Journal of the American Geriatrics Society · 2025Article
- Predictors of Adverse Drug Reaction-Related Hospitalisations Among People with Dementia: A Retrospective Case-Control Study.Drug safety · 2024Article
- Drug-related problems and associated factors among patients with kidney dysfunction at a tertiary hospital in southwestern Uganda: a prospective observational study.BMC nephrology · 2023Observational
- Adverse drug reactions in hospitals: population estimates for Portugal and the ICD-9-CM to ICD-10-CM crosswalk.BMC health services research · 2023Article
- Sharing Adverse Drug Event Reports Between Hospitals and Community Pharmacists to Inform Re-dispensing: An Analysis of Reports and Process Outcomes.Drug safety · 2023Observational
- Validating ICD-10 codes for adverse drug events in hospitalised older adults: protocol for a cross-sectional study.BMJ open · 2022Article
- Evaluation of Factors Associated with Adverse Drug Events in South Korea Using a Population-Based Database.Journal of clinical medicine · 2022Article
- Shortcomings of Administrative Data to Derive Preventive Strategies for Inhospital Drug-Induced Acute Kidney Failure-Insights from Patient Record Analysis.Journal of clinical medicine · 2022Article
- Persistence of Adverse Drug Reaction-Related Hospitalization Risk Following Discharge.International journal of environmental research and public health · 2022Article
- Applying Machine Learning in Distributed Data Networks for Pharmacoepidemiologic and Pharmacovigilance Studies: Opportunities, Challenges, and Considerations.Drug safety · 2022Review
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
backgroundAdverse drug events are a frequent cause of emergency department presentations. Administrative data could be used to identify patients presenting with adverse drug events for post-market surveillance, and to conduct research in patient safety and in drug safety and effectiveness. However, such data sources have not been evaluated for their completeness with regard to adverse drug event reporting. Our objective was to determine the proportion of adverse drug events to outpatient medications diagnosed at the point-of-care in emergency departments that were documented in administrative data.
methodsWe linked the records of patients enrolled in a prospective observational cohort study on adverse drug events conducted in two Canadian tertiary care emergency departments to their administrative data. We compared the number of adverse drug events diagnosed and recorded at the point-of-care in the prospective study with the number of adverse drug events recorded in the administrative data.
resultsAmong 1574 emergency department visits, 221 were identified as adverse drug event-related in the prospective database. We found 15 adverse drug events documented in administrative records with ICD-10 codes clearly indicating an adverse drug event, indicating a sensitivity of 6.8% (95% CI 4.0-11.2%) of this code set. When the ICD-10 code categories were broadened to include codes indicating a very likely, likely or possible adverse event to a medication, 62 of 221 events were identifiable in administrative data, corresponding to a sensitivity of 28.1% (95% CI 22.3-34.6%).
conclusionsAdverse drug events to outpatient medications were underreported in emergency department administrative data compared to the number of adverse drug events diagnosed and recorded at the point-of-care.
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